SCHEMBL29657487

SCHEMBL29657487

CC1CCC(C(C)C)C(CCc2ccccn2)(C(N)=O)C1

nearest known ligand 0.41

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.40
HSD11B1 P28845 2/20 0.40
CYP1A2 P05177 1/20 0.39
HTT P42858 1/20 0.38
ATM Q13315 1/20 0.38
ALDH1A1 P00352 4/20 0.37
HRH2 P25021 1/20 0.37
TSHR P16473 2/20 0.36
TAS1R3 Q7RTX0 1/20 0.36
TAS1R1 Q7RTX1 1/20 0.36
MAPK1 P28482 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
P2RX7 Q99572 1/20 0.36
CYP3A4 P08684 1/20 0.36
LMNA P02545 1/20 0.36
TDP1 Q9NUW8 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3457775 0.89 HSD11B1 (0.42) SMN1; SMN2HSD11B1CYP1A2HTTATM
SCHEMBL29141636 0.81 HSD11B1 (0.52) SMN1; SMN2HSD11B1CYP1A2HTTATM
SCHEMBL29112390 0.77 HSD11B1 (0.54) SMN1; SMN2HSD11B1CYP1A2HTTATM
SCHEMBL24540861 0.77 HSD11B1 (0.54) SMN1; SMN2HSD11B1CYP1A2HTTATM
SCHEMBL29112392 0.77 HSD11B1 (0.54) SMN1; SMN2HSD11B1CYP1A2HTTATM
SCHEMBL20815347 0.75 SMN1; SMN2 (0.40) SMN1; SMN2HSD11B1CYP1A2HTTATM
SCHEMBL28802591 0.74 EPHX1 (0.34)
SCHEMBL28608870 0.70
SCHEMBL29603931 0.69 HSD11B1 (0.39) HSD11B1CYP1A2HTTATMALDH1A1
SCHEMBL14872134 0.68 EPHX1 (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022145163-A1 COMPOSITION FOR ORAL CAVITY ライオン株式会社 2022-07-07 WO disclosed