Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | APAF1 | O14727 | 1/20 | 0.48 |
| ▸ | HK1 | P19367 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CLK1 | P49759 | 4/20 | 0.46 |
| ▸ | DYRK1A | Q13627 | 4/20 | 0.46 |
| ▸ | CLK4 | Q9HAZ1 | 4/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8690556 | 0.99 | LTA4H (0.55) | LTA4HALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL22792280 | 0.75 | ALDH1A1 (0.50) | LTA4HALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL5605047 | 0.74 | LTA4H (0.82) | LTA4HALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL30642394 | 0.73 | LTA4H (1.00) | LTA4HALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL523753 | 0.73 | LTA4H (1.00) | LTA4HALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL22792637 | 0.72 | LTA4H (0.61) | LTA4HALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL22191758 | 0.72 | LTA4H (0.61) | LTA4HALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL4180572 | 0.72 | LTA4H (0.61) | LTA4HALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL13428028 | 0.71 | LTA4H (0.65) | LTA4HALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL2462206 | 0.70 | KMT2A (0.51) | LTA4HALDH1A1MAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110123820-B | Arginase inhibitors and methods of use thereof | 阿斯利康公司 | 2022-05-31 | — | — | CN | disclosed |