Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | LTA4H | P09960 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | PGK1 | P00558 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | PDE4A | P27815 | 1/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.44 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22792275 | 0.78 | MEN1 (0.52) | ALDH1A1MEN1KMT2AL3MBTL1POLB | |
| SCHEMBL29657492 | 0.75 | LTA4H (0.56) | ALDH1A1LTA4HMEN1KMT2AMAPT | |
| Hydrochloric Acid SCHEMBL8690556 | 0.74 | LTA4H (0.55) | ALDH1A1LTA4HMEN1KMT2AMAPT | |
| SCHEMBL2908596 | 0.73 | ALDH1A1 (0.69) | ALDH1A1LTA4HMEN1KMT2AMAPT | |
| SCHEMBL3122746 | 0.72 | L3MBTL1 (0.67) | ALDH1A1LTA4HMEN1KMT2AMAPT | |
| SCHEMBL19312422 | 0.72 | LTA4H (0.60) | ALDH1A1LTA4HMEN1KMT2AMAPT | |
| SCHEMBL22792726 | 0.71 | LTA4H (0.55) | ALDH1A1LTA4HMEN1KMT2AMAPT | |
| SCHEMBL22792298 | 0.70 | CYP1A2 (0.53) | ALDH1A1MEN1KMT2AL3MBTL1POLB | |
| SCHEMBL5605047 | 0.70 | LTA4H (0.82) | ALDH1A1LTA4HMEN1KMT2AMAPT | |
| SCHEMBL10750744 | 0.69 | SMN1; SMN2 (0.53) | ALDH1A1LTA4HKMT2AL3MBTL1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020252229-A2 | INHIBITORS OF SARM1 | DISARM THERAPEUTICS, INC. (US) | 2020-12-17 | — | — | WO | disclosed |