Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB8 | P28062 | 1/20 | 0.46 |
| ▸ | PARP1 | P09874 | 3/20 | 0.45 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.43 |
| ▸ | CDK4 | P11802 | 3/20 | 0.43 |
| ▸ | CCND1 | P24385 | 3/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | DAO | P14920 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MGAM | O43451 | 1/20 | 0.39 |
| ▸ | SI | P14410 | 1/20 | 0.39 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.39 |
| ▸ | PTGES | O14684 | 1/20 | 0.39 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28739893 | 0.86 | PSMB8 (0.36) | PSMB8PARP1CHEK1CDK4CCND1 | |
| SCHEMBL2358644 | 0.79 | PARP1 (0.53) | PSMB8PARP1CHEK1ADORA1MAOB | |
| SCHEMBL7456831 | 0.78 | PSMB8 (0.53) | PSMB8PARP1CHEK1ADORA1MAOB | |
| SCHEMBL4173826 | 0.75 | PSMB8 (0.46) | PSMB8PARP1CHEK1ADORA1MAOB | |
| SCHEMBL13768217 | 0.73 | KDM4E (0.60) | GAALMNAMEN1HPGDKMT2A | |
| SCHEMBL8265192 | 0.71 | PARP1 (0.59) | PSMB8PARP1CHEK1ADORA1MAOB | |
| SCHEMBL1170768 | 0.70 | ADORA1 (0.61) | PSMB8PARP1ADORA1MAOBADORA2A | |
| SCHEMBL66295 | 0.70 | PSMB8 (0.59) | PSMB8PARP1ADORA1MAOBADORA2A | |
| SCHEMBL2779501 | 0.68 | MAP3K5 (0.46) | PARP1CHEK1ADORA3GAALMNA | |
| SCHEMBL215756 | 0.67 | NUDT1 (0.70) | PSMB8ADORA1MAOBADORA2AADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112480016-B | (E) -1-acyl-1- (3-quinoxalinone) methyl ketoxime and synthesis method thereof | 杭州师范大学 | 2022-05-20 | — | — | CN | disclosed |