SCHEMBL2965759

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL445944	0.87	SIGMAR1 (0.48)	SIGMAR1HTR1AKCNH2CTSKALDH1A1
	SCHEMBL447632	0.85	SIGMAR1 (0.50)	SIGMAR1HTR1AKCNH2CTSKALDH1A1
	SCHEMBL545449	0.84	LMNA (0.53)	NR1H2MAPTALDH1A1CYP3A4CYP1A2
	SCHEMBL29777509	0.84	LMNA (0.53)	NR1H2MAPTALDH1A1CYP3A4CYP1A2
	SCHEMBL2795945	0.74	TAAR1 (0.41)	NOS3NOS1NOS2MAPK1TSHR
	SCHEMBL2793246	0.74	TAAR1 (0.41)	NOS3NOS1MAPK1TSHRRAD52
	SCHEMBL3150811	0.74	SIGMAR1 (0.76)	SIGMAR1HTR1ADRD2ADRA2CSLC6A4
	SCHEMBL428036	0.73	SIGMAR1 (0.51)	SIGMAR1NOS3NOS1KCNH2CTSK
	SCHEMBL449503	0.73	RPS6KB1 (0.39)	NR1H2ALDH1A1SLC6A2SLC6A4HRH3
	SCHEMBL29543344	0.72	ALDH1A1 (0.47)	NR1H2MAPTALDH1A1CYP3A4CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.