Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.60 |
| ▸ | MAPT | P10636 | 7/20 | 0.60 |
| ▸ | RAB9A | P51151 | 6/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.60 |
| ▸ | GLA | P06280 | 3/20 | 0.60 |
| ▸ | GAA | P10253 | 3/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.60 |
| ▸ | PPARG | P37231 | 1/20 | 0.60 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.60 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.60 |
| ▸ | ERN1 | O75460 | 2/20 | 0.59 |
| ▸ | NPC1 | O15118 | 6/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.57 |
| ▸ | TP53 | P04637 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.57 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.57 |
| ▸ | RELA | Q04206 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28735235 | 1.00 | KDM4E (0.60) | KDM4EMAPTRAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL30466258 | 0.82 | KDM4E (0.69) | KDM4EMAPTRAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL12470903 | 0.82 | KDM4E (0.69) | KDM4EMAPTRAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL28590372 | 0.82 | KDM4E (0.58) | KDM4EMAPTRAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL23723 | 0.82 | KDM4E (0.58) | KDM4EMAPTRAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL25288484 | 0.80 | KDM4E (0.71) | KDM4EMAPTRAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL12471564 | 0.78 | KDM4E (0.64) | KDM4EMAPTRAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL4592655 | 0.78 | KDM4E (0.64) | KDM4EMAPTRAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL11193289 | 0.78 | RAB9A (0.66) | KDM4EMAPTRAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL8373442 | 0.78 | MAPT (0.68) | KDM4EMAPTRAB9AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114478514-B | Fluorescent molecular probe with aggregation-induced emission characteristic and preparation method and application thereof | 湖南省肿瘤医院 | 2023-04-18 | — | — | CN | claimed |
| CN-110172337-B | Benzothiazole derivative fluorescent probe and preparation method and application thereof | 南京师范大学 | 2022-09-13 | — | — | CN | claimed |
| CN-114478514-A | Fluorescent molecular probe with aggregation-induced emission characteristic and preparation method and application thereof | 湖南省肿瘤医院 | 2022-05-13 | — | — | CN | claimed |
| CN-114478514-B | Fluorescent molecular probe with aggregation-induced emission characteristic and preparation method and application thereof | 湖南省肿瘤医院 | 2023-04-18 | — | — | CN | disclosed |
| CN-110172337-B | Benzothiazole derivative fluorescent probe and preparation method and application thereof | 南京师范大学 | 2022-09-13 | — | — | CN | disclosed |
| CN-114478514-A | Fluorescent molecular probe with aggregation-induced emission characteristic and preparation method and application thereof | 湖南省肿瘤医院 | 2022-05-13 | — | — | CN | disclosed |