Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RBP4 | P02753 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 2/20 | 0.39 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.38 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.38 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.38 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.37 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28735359 | 1.00 | RBP4 (0.43) | RBP4MAOAMAOBALDH1A1MAPT | |
| SCHEMBL29658393 | 0.86 | ALDH1A1 (0.41) | RBP4ALDH1A1MAPTCHRNB1CHRNB2 | |
| SCHEMBL28735484 | 0.86 | ALDH1A1 (0.41) | RBP4ALDH1A1MAPTCHRNB1CHRNB2 | |
| SCHEMBL2203963 | 0.81 | MET (0.45) | MAOAMAOBALDH1A1MAPTKDR | |
| SCHEMBL24566899 | 0.80 | BRAF (0.41) | KDR | |
| SCHEMBL16895232 | 0.80 | BRAF (0.41) | KDR | |
| SCHEMBL24566589 | 0.80 | BRAF (0.41) | KDR | |
| SCHEMBL450027 | 0.80 | CHRNB4 (0.60) | CHRNB1CHRNB2CHRNB4CHRNA3CHRNB3 | |
| SCHEMBL447762 | 0.80 | CHRNB4 (0.60) | CHRNB1CHRNB2CHRNB4CHRNA3CHRNB3 | |
| SCHEMBL447049 | 0.80 | CHRNB4 (0.60) | CHRNB1CHRNB2CHRNB4CHRNA3CHRNB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114478366-A | Pyridone derivative and application thereof in medicine | 海思科医药集团股份有限公司 | 2022-05-13 | — | — | CN | disclosed |