Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.45 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | GABBR2 | O75899 | 3/20 | 0.44 |
| ▸ | GABBR1 | Q9UBS5 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19717863 | 1.00 | BRD4 (0.45) | BRD4HDAC4HDAC7HDAC5MAPT | |
| SCHEMBL5068690 | 1.00 | BRD4 (0.45) | BRD4HDAC4HDAC7HDAC5MAPT | |
| SCHEMBL5068688 | 1.00 | BRD4 (0.45) | BRD4HDAC4HDAC7HDAC5MAPT | |
| SCHEMBL29386802 | 0.81 | BRD4 (0.48) | BRD4HDAC4HDAC7HDAC5MAPT | |
| SCHEMBL22082538 | 0.79 | LMNA (0.39) | MAPTSMN1; SMN2LMNACYP2C9TSHR | |
| SCHEMBL22082536 | 0.79 | LMNA (0.39) | MAPTSMN1; SMN2LMNACYP2C9TSHR | |
| SCHEMBL6367 | 0.79 | LMNA (0.62) | BRD4HDAC4HDAC7HDAC5NPSR1 | |
| SCHEMBL20853599 | 0.79 | BRD4 (0.47) | BRD4HDAC4HDAC7HDAC5MAPT | |
| SCHEMBL22081099 | 0.79 | LMNA (0.39) | MAPTSMN1; SMN2LMNACYP2C9TSHR | |
| SCHEMBL6366 | 0.79 | LMNA (0.62) | BRD4HDAC4HDAC7HDAC5NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109563043-B | Substituted pyridines as inhibitors of DNMT1 | 葛兰素史密斯克莱知识产权发展有限公司 | 2022-05-31 | — | — | CN | disclosed |