Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.34 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.34 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.33 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.33 |
| ▸ | MET | P08581 | 1/20 | 0.33 |
| ▸ | MST1R | Q04912 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | F10 | P00742 | 1/20 | 0.32 |
| ▸ | BTK | Q06187 | 1/20 | 0.31 |
| ▸ | APLNR | P35414 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19716584 | 1.00 | EPHX2 (0.36) | EPHX2P2RX7FOLH1KCNQ3KCNQ2 | |
| SCHEMBL2761040 | 0.80 | P2RX7 (0.37) | P2RX7METMST1RAPLNR | |
| SCHEMBL2760832 | 0.77 | TRPV4 (0.43) | P2RX7CES2CES1 | |
| SCHEMBL19544649 | 0.76 | CYP2A6 (0.36) | EPHX2P2RX7FOLH1KCNQ3KCNQ2 | |
| SCHEMBL4092644 | 0.74 | HDAC3 (0.45) | CES2CES1 | |
| SCHEMBL19735013 | 0.74 | HDAC3 (0.45) | CES2CES1 | |
| SCHEMBL3554668 | 0.73 | EPHX2 (0.41) | EPHX2P2RX7FOLH1KCNQ3KCNQ2 | |
| SCHEMBL19716738 | 0.73 | LOXL2 (0.39) | METMST1RCES2CES1F10 | |
| SCHEMBL29658521 | 0.73 | LOXL2 (0.39) | METMST1RCES2CES1F10 | |
| SCHEMBL19716826 | 0.73 | FOLH1 (0.32) | EPHX2P2RX7FOLH1APLNR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109563043-B | Substituted pyridines as inhibitors of DNMT1 | 葛兰素史密斯克莱知识产权发展有限公司 | 2022-05-31 | — | — | CN | disclosed |