Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 2/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | MAPT | P10636 | 3/20 | 0.62 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | EDNRB | P24530 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | PDE4A | P27815 | 1/20 | 0.54 |
| ▸ | AGO2 | Q9UKV8 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | HTR6 | P50406 | 2/20 | 0.49 |
| ▸ | TERT | O14746 | 1/20 | 0.48 |
| ▸ | CDK2 | P24941 | 2/20 | 0.48 |
| ▸ | CDC7 | O00311 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7211420 | 0.85 | EDNRA (0.74) | EDNRAALDH1A1MAPTEDNRBTP53 | |
| SCHEMBL7217887 | 0.84 | EDNRA (0.72) | EDNRAMAPTTSHREDNRBTP53 | |
| SCHEMBL5565400 | 0.81 | EDNRA (0.68) | EDNRAALDH1A1MAPTSMN1; SMN2CYP2C9 | |
| SCHEMBL7217783 | 0.79 | EDNRA (0.65) | EDNRAALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL7212749 | 0.78 | EDNRA (0.64) | EDNRAMAPTTSHRTP53CDK2 | |
| SCHEMBL27508434 | 0.78 | EDNRA (0.64) | EDNRAALDH1A1MAPTCYP2C9TSHR | |
| SCHEMBL7211689 | 0.78 | EDNRA (0.64) | EDNRAMAPTTSHREDNRBTP53 | |
| SCHEMBL6151676 | 0.77 | EDNRA (0.62) | EDNRAALDH1A1MAPTSMN1; SMN2TSHR | |
| Sulfamethoxazole SCHEMBL3656 | 0.77 | ALDH1A1 (1.00) | EDNRAALDH1A1MAPTADRA1ACYP2C9 | |
| Sulfamethoxazole SCHEMBL6896861 | 0.77 | ALDH1A1 (1.00) | EDNRAALDH1A1MAPTADRA1ACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111007191-B | Content of sulfamethoxazole and/or trimethoprim, detection method of related substances thereof and application thereof | 北京振东光明药物研究院有限公司 | 2022-07-08 | — | — | CN | disclosed |