Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.37 |
| ▸ | MAP2K3 | P46734 | 1/20 | 0.37 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.36 |
| ▸ | CLK2 | P49760 | 1/20 | 0.36 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18548670 | 0.86 | MGAM (0.46) | ALDH1A1NPSR1POLBKDM4EPTPN2 | |
| SCHEMBL29660196 | 0.86 | MGAM (0.46) | ALDH1A1NPSR1POLBKDM4EPTPN2 | |
| SCHEMBL18561326 | 0.81 | ALDH1A1 (0.36) | ALDH1A1NPSR1POLBKDM4EPTPN2 | |
| SCHEMBL29660200 | 0.77 | CYP1A2 (0.51) | ALDH1A1KDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL18548710 | 0.77 | CYP1A2 (0.51) | ALDH1A1KDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL22633448 | 0.75 | RAD51 (0.45) | ALDH1A1NPSR1KDM4EPTPN2PTPN1 | |
| SCHEMBL2163722 | 0.75 | PTPN1 (0.44) | ALDH1A1NPSR1POLBKDM4EPTPN2 | |
| SCHEMBL29660167 | 0.74 | ADORA2A (0.44) | ALDH1A1POLBKDM4EADORA2AADORA1 | |
| SCHEMBL18548681 | 0.74 | ADORA2A (0.44) | ALDH1A1POLBKDM4EADORA2AADORA1 | |
| SCHEMBL18548648 | 0.73 | ADORA2A (0.62) | ALDH1A1KDM4EADORA2AADORA1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11344637-B2 | Probes for imaging huntingtin protein | CHDI FOUNDATION, INC. (US) | 2022-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11344637-B2 | Probes for imaging huntingtin protein | HTT, HYPK, HSPBP1 | ALDH1A1 3976/4885NPSR1 885/4885POLB 3501/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.