Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.31 |
| ▸ | POLL | Q9UGP5 | 1/20 | 0.31 |
| ▸ | FNTA | P49354 | 5/20 | 0.31 |
| ▸ | FNTB | P49356 | 5/20 | 0.31 |
| ▸ | STS | P08842 | 1/20 | 0.30 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.30 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.30 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.30 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.30 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15287132 | 1.00 | MAP3K14 (0.34) | MAP3K14OPRM1OPRL1CYP11B1CYP11B2 | |
| SCHEMBL11352700 | 0.81 | NOTUM (0.37) | MAP3K14OPRM1OPRL1CYP11B1CYP11B2 | |
| SCHEMBL22102575 | 0.78 | OPRM1 (0.34) | MAP3K14OPRM1OPRL1CYP11B1CYP11B2 | |
| SCHEMBL22102913 | 0.78 | OPRL1 (0.37) | MAP3K14OPRM1OPRL1CYP11B1CYP11B2 | |
| SCHEMBL22102579 | 0.78 | MAP3K14 (0.34) | MAP3K14OPRM1OPRL1CYP11B1CYP11B2 | |
| SCHEMBL22103239 | 0.78 | MAP3K14 (0.34) | MAP3K14OPRM1OPRL1CYP11B1CYP11B2 | |
| SCHEMBL15287108 | 0.78 | CYP11B1 (0.37) | MAP3K14CYP11B1CYP11B2POLLSTS | |
| SCHEMBL15021555 | 0.78 | CYP11B1 (0.37) | MAP3K14CYP11B1CYP11B2POLLSTS | |
| SCHEMBL35211487 | 0.78 | CYP11B1 (0.37) | MAP3K14CYP11B1CYP11B2POLLSTS | |
| SCHEMBL1508379 | 0.77 | HTR2C (0.45) | MAP3K14OPRM1OPRL1POLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119497712-A | Indane derivatives as MALT1 inhibitors | 希四克斯探索有限公司 | 2025-02-21 | — | — | CN | disclosed |
| CN-113195492-B | Novel compound with three-fused ring structure, preparation method and application thereof | 信达生物制药(苏州)有限公司 | 2022-07-08 | — | — | CN | disclosed |