SCHEMBL29660490

SCHEMBL29660490

NCC(=O)Nc1ccc2c(c1)C(=O)OC21c2ccc(O)cc2Oc2cc(O)ccc21

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FTO Q9C0B1 9/20 0.74
MEN1 O00255 1/20 0.59
MAPT P10636 1/20 0.59
HPGD P15428 1/20 0.59
CYP2C19 P33261 1/20 0.59
HTT P42858 1/20 0.59
RECQL P46063 1/20 0.59
BLM P54132 1/20 0.59
SMAD3 P84022 1/20 0.59
KMT2A Q03164 1/20 0.59
PRMT1 Q99873 1/20 0.59
ACE2 Q9BYF1 1/20 0.59
TDP1 Q9NUW8 1/20 0.59
DRD1 P21728 3/20 0.48
KCNH2 Q12809 1/20 0.47
NAALAD2 Q9Y3Q0 1/20 0.47
JAK2 O60674 2/20 0.46
TERT O14746 1/20 0.46
TTR P02766 1/20 0.46
NR5A2 O00482 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL392368 1.00 FTO (0.74) FTOMEN1MAPTHPGDCYP2C19
SCHEMBL7038220 0.90 FTO (0.72) FTOMEN1MAPTHPGDCYP2C19
SCHEMBL9626320 0.89 FTO (0.74) FTOMEN1MAPTHPGDCYP2C19
SCHEMBL7611076 0.89 FTO (0.74) FTOMEN1MAPTHPGDCYP2C19
SCHEMBL17970938 0.89 FTO (0.74) FTOMEN1MAPTHPGDCYP2C19
SCHEMBL29406840 0.89 FTO (0.78) FTOMEN1MAPTHPGDCYP2C19
SCHEMBL9428406 0.89 FTO (0.74) FTOMEN1MAPTHPGDCYP2C19
SCHEMBL25103 0.89 FTO (0.78) FTOMEN1MAPTHPGDCYP2C19
SCHEMBL13537269 0.87 FTO (0.69) FTOMEN1MAPTHPGDCYP2C19
SCHEMBL15658275 0.87 FTO (0.71) FTOMEN1MAPTHPGDCYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4348347-A2 SYSTEM AND METHOD FOR HIGH RESOLUTION 3D NANOFABRICATION Irradiant Technologies Inc. (US) 2024-04-10 EP claimed
CN-117813548-A System and method for high resolution three-dimensional nanofabrication 光辉科技股份有限公司 2024-04-02 CN claimed
WO-2022251546-A2 SYSTEM AND METHOD FOR HIGH RESOLUTION 3D NANOFABRICATION Irradiant Technologies Inc. (US) 2022-12-01 WO claimed
EP-3430015-B1 METHODS TO DETERMINE KDM1A TARGET ENGAGEMENT AND CHEMOPROBES USEFUL THEREFOR ORYZON GENOMICS SA (ES) 2025-08-06 EP disclosed
US-12195783-B2 Methods to determine KDM1A target engagement and chemoprobes useful therefor ORYZON GENOMICS S.A. (ES) 2025-01-14 US disclosed
CN-118084813-A Macrocyclic compounds 诺和诺德牛津研究中心有限公司 2024-05-28 CN disclosed
CN-110691777-B Macrocyclic compounds 诺和诺德牛津研究中心有限公司 2024-03-01 CN disclosed
US-20220389478-A1 METHODS TO DETERMINE KDM1A TARGET ENGAGEMENT AND CHEMOPROBES USEFUL THEREFOR ORYZON GENOMICS SA (ES) 2022-12-08 US disclosed
EP-4010707-A1 METHODS FOR DETECTING ASSAY INTERFERENTS AND INCREASING DYNAMIC RANGE Abbott Laboratories (US) 2022-06-15 EP disclosed
EP-4010433-A1 CHEMILUMINESCENT COMPOUNDS FOR MULTIPLEXING Abbott Laboratories (US) 2022-06-15 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220389478-A1 METHODS TO DETERMINE KDM1A TARGET ENGAGEMENT AND CHEMOPROBES USEFUL THEREFOR KDM1B, KDM1A, KDM7A FTO 778/4885MEN1 2238/4885MAPT 4545/4885
US-12195783-B2 Methods to determine KDM1A target engagement and chemoprobes useful therefor KDM1B, KDM1A, KDM7A FTO 778/4885MEN1 2238/4885MAPT 4545/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.