Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FTO | Q9C0B1 | 9/20 | 0.74 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | RECQL | P46063 | 1/20 | 0.59 |
| ▸ | BLM | P54132 | 1/20 | 0.59 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.59 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | DRD1 | P21728 | 5/20 | 0.50 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.49 |
| ▸ | TTR | P02766 | 1/20 | 0.48 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.47 |
| ▸ | JAK2 | O60674 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 3/20 | 0.46 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7606796 | 0.92 | FTO (0.63) | FTOMEN1MAPTHPGDCYP2C19 | |
| SCHEMBL25103 | 0.89 | FTO (0.78) | FTOMEN1MAPTHPGDCYP2C19 | |
| SCHEMBL392368 | 0.89 | FTO (0.74) | FTOMEN1MAPTHPGDCYP2C19 | |
| SCHEMBL29406840 | 0.89 | FTO (0.78) | FTOMEN1MAPTHPGDCYP2C19 | |
| SCHEMBL9428406 | 0.89 | FTO (0.74) | FTOMEN1MAPTHPGDCYP2C19 | |
| SCHEMBL17970938 | 0.89 | FTO (0.74) | FTOMEN1MAPTHPGDCYP2C19 | |
| SCHEMBL9626320 | 0.89 | FTO (0.74) | FTOMEN1MAPTHPGDCYP2C19 | |
| SCHEMBL29660490 | 0.89 | FTO (0.74) | FTOMEN1MAPTHPGDCYP2C19 | |
| SCHEMBL10400640 | 0.88 | FTO (0.77) | FTOMEN1MAPTHPGDCYP2C19 | |
| SCHEMBL7038220 | 0.88 | FTO (0.72) | FTOMEN1MAPTHPGDCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0853628-B1 | PHOTOLABILE 8-SUBSTITUTED CYCLIC NUCLEOTIDE ESTERS, METHODS OF PREPARING THEM AND THEIR USE | FORSCHUNGSVERBUND BERLIN EV (DE) | 2002-10-02 | — | — | EP | claimed |
| EP-0853628-A1 | PHOTOLABILE 8-SUBSTITUTED CYCLIC NUCLEOTIDE ESTERS, METHODS OF PREPARING THEM AND THEIR USE | Forschungsverbund Berlin e.V. (DE) | 1998-07-22 | — | — | EP | claimed |
| WO-1997005155-A1 | PHOTOLABILE 8-SUBSTITUTED CYCLIC NUCLEOTIDE ESTERS, METHODS OF PREPARING THEM AND THEIR USE | FORSCHUNGSVERBUND BERLIN E.V. (DE) | 1997-02-13 | — | — | WO | claimed |
| EP-0853628-B1 | PHOTOLABILE 8-SUBSTITUTED CYCLIC NUCLEOTIDE ESTERS, METHODS OF PREPARING THEM AND THEIR USE | FORSCHUNGSVERBUND BERLIN EV (DE) | 2002-10-02 | — | — | EP | disclosed |
| EP-0853628-A1 | PHOTOLABILE 8-SUBSTITUTED CYCLIC NUCLEOTIDE ESTERS, METHODS OF PREPARING THEM AND THEIR USE | Forschungsverbund Berlin e.V. (DE) | 1998-07-22 | — | — | EP | disclosed |
| WO-1997005155-A1 | PHOTOLABILE 8-SUBSTITUTED CYCLIC NUCLEOTIDE ESTERS, METHODS OF PREPARING THEM AND THEIR USE | FORSCHUNGSVERBUND BERLIN E.V. (DE) | 1997-02-13 | — | — | WO | disclosed |