Sugi Predict

Sugi Predict / Compounds / SCHEMBL25103

SCHEMBL25103

SCHEMBL25103

O=C(CI)Nc1ccc2c(c1)C(=O)OC21c2ccc(O)cc2Oc2cc(O)ccc21

nearest known ligand 0.78

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ FTO Q9C0B1 9/20 0.78
▸ MEN1 O00255 1/20 0.59
▸ MAPT P10636 1/20 0.59
▸ HPGD P15428 1/20 0.59
▸ CYP2C19 P33261 1/20 0.59
▸ HTT P42858 1/20 0.59
▸ RECQL P46063 1/20 0.59
▸ BLM P54132 1/20 0.59
▸ SMAD3 P84022 1/20 0.59
▸ KMT2A Q03164 1/20 0.59
▸ PRMT1 Q99873 1/20 0.59
▸ ACE2 Q9BYF1 1/20 0.59
▸ TDP1 Q9NUW8 1/20 0.59
▸ DRD1 P21728 5/20 0.48
▸ NAALAD2 Q9Y3Q0 1/20 0.47
▸ TTR P02766 1/20 0.46
▸ KCNH2 Q12809 1/20 0.46
▸ JAK2 O60674 1/20 0.45
▸ DRD2 P14416 3/20 0.44
▸ KEAP1 Q14145 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29406840 1.00 FTO (0.78) FTOMEN1MAPTHPGDCYP2C19
SCHEMBL29399629 0.92 FTO (0.66) FTOMEN1MAPTHPGDCYP2C19
SCHEMBL1286244 0.92 FTO (0.66) FTOMEN1MAPTHPGDCYP2C19
SCHEMBL28241690 0.90 FTO (0.69) FTOMEN1MAPTHPGDCYP2C19
SCHEMBL392368 0.89 FTO (0.74) FTOMEN1MAPTHPGDCYP2C19
SCHEMBL7611076 0.89 FTO (0.74) FTOMEN1MAPTHPGDCYP2C19
SCHEMBL29660490 0.89 FTO (0.74) FTOMEN1MAPTHPGDCYP2C19
SCHEMBL9626320 0.89 FTO (0.74) FTOMEN1MAPTHPGDCYP2C19
SCHEMBL9428406 0.89 FTO (0.74) FTOMEN1MAPTHPGDCYP2C19
SCHEMBL17970938 0.89 FTO (0.74) FTOMEN1MAPTHPGDCYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1032 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12116627-B2 Methods of sequencing and producing nucleic acid sequences TSINGHUA UNIVERSITY (CN) 2024-10-15 — — US claimed
US-12105092-B2 Molecularly imprinted particles GEORGE MASON UNIVERSITY (US) 2024-10-01 — — US claimed
US-20240316171-A1 COMPOSITIONS AND METHODS FOR TARGETED IMMUNOTHERAPY DANA FARBER CANCER INST INC (US) 2024-09-26 — — US claimed
CN-118408917-A Intracellular sulfhydryl protein imaging method based on N, N-dimethylacrylamide polymerized monomer expansion microscope 西安交通大学 2024-07-30 — — CN claimed
US-20240168032-A1 GLUCOSE BIOSENSORS AND USES THEREOF UNIV DUKE (US) 2024-05-23 — — US claimed
EP-3377898-B1 THERMOSTABLE GLUCOSE BIOSENSORS AND USES THEREOF UNIV DUKE (US) 2024-05-01 — — EP claimed
EP-3377904-B1 UREA BIOSENSORS AND USES THEREOF UNIV DUKE (US) 2024-05-01 — — EP claimed
EP-3377897-B1 LACTATE BIOSENSORS AND USES THEREOF UNIV DUKE (US) 2024-05-01 — — EP claimed
CN-117625661-A PafA inhibitor screening model and construction method and application thereof 重庆医科大学 2024-03-01 — — CN claimed
US-11852637-B2 Bicarbonate biosensors, calcium biosensors, and uses thereof DUKE UNIVERSITY (US) 2023-12-26 — — US claimed
EP-1335984-A1 DETERMINATION OF HYDROPHOBIC COENZYME A ESTERS AND OTHER LIPIDS USING A BIOSENSOR COMPRISING A MODIFIED COENZYME A- AND ACYL-COA BINDING PROTEIN (ACBP) Biosensor APS (DK) 2003-08-20 — — EP claimed
US-20030153012-A1 Biosensors, method for obtaining the same and uses thereof INSTITUT PASTEUR (FR) 2003-08-14 — — US claimed
WO-2003014343-A1 METHOD FOR ANALYZING INHIBITION OF FTSZ POLYMERIZATION USING FLUORESCENCE ASSAY TECHNIQUE MERCK & CO., INC. (US) 2003-02-20 — — WO claimed
EP-1259809-A1 BIOSENSORS, METHOD FOR OBTAINING SAME AND USES THEREOF INSTITUT PASTEUR (FR) 2002-11-27 — — EP claimed
US-20020142347-A1 Biosensor BIOSENSOR APS (DK) 2002-10-03 — — US claimed
EP-1238116-A1 PROCESS FOR LABELING A NUCLEIC ACID BIO MERIEUX (FR) 2002-09-11 — — EP claimed
WO-2002061096-A1 DETERMINATION OF HYDROPHOBIC COENZYME A ESTERS AND OTHER LIPIDS USING A BIOSENS OR COMPRISING A MODIFIED COENZYME A- AND ACYL- BINDING PROTEIN (ACBP) BIOSENSOR APS (DK) 2002-08-08 — — WO claimed
US-20020081586-A1 Process for labeling a nucleic acid HOLOGIC, INC. 2002-06-27 — — US claimed
WO-2001065258-A1 BIOSENSORS, METHOD FOR OBTAINING SAME AND USES THEREOF INSTITUT PASTEUR (FR) 2001-09-07 — — WO claimed
WO-2001044507-A1 PROCESS FOR LABELING A NUCLEIC ACID BIO MERIEUX (FR) 2001-06-21 — — WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240168032-A1 GLUCOSE BIOSENSORS AND USES THEREOF GCK, GCKR, SLC2A4 FTO 94/4885MEN1 2391/4885MAPT 1875/4885
US-20240316171-A1 COMPOSITIONS AND METHODS FOR TARGETED IMMUNOTHERAPY TP53, CD47, MSH2 FTO 3211/4885MEN1 1807/4885MAPT 1095/4885
US-11852637-B2 Bicarbonate biosensors, calcium biosensors, and uses thereof CA2, CASR, CACYBP FTO 1195/4885MEN1 1448/4885MAPT 4652/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.