Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.71 |
| ▸ | MEN1 | O00255 | 2/20 | 0.71 |
| ▸ | LMNA | P02545 | 1/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.63 |
| ▸ | HTT | P42858 | 1/20 | 0.63 |
| ▸ | NPC1 | O15118 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4661701 | 1.00 | GAA (0.72) | GAAKMT2AMEN1LMNAKDM4E | |
| SCHEMBL12793682 | 0.89 | GAA (0.71) | GAAKMT2AMEN1LMNAKDM4E | |
| SCHEMBL5466124 | 0.88 | LMNA (0.70) | GAAKMT2AMEN1LMNAKDM4E | |
| SCHEMBL13712057 | 0.86 | GAA (0.67) | GAAKMT2AMEN1LMNAKDM4E | |
| SCHEMBL6607377 | 0.85 | GAA (0.62) | GAAKMT2AMEN1LMNAKDM4E | |
| SCHEMBL9812951 | 0.84 | GAA (0.69) | GAAKMT2AMEN1LMNAPOLB | |
| SCHEMBL28279207 | 0.84 | TP53 (0.67) | GAAKMT2AMEN1LMNAKDM4E | |
| SCHEMBL5597888 | 0.83 | GAA (0.71) | GAAKMT2AMEN1LMNAKDM4E | |
| SCHEMBL5466121 | 0.83 | GAA (0.64) | GAAKMT2AMEN1LMNAKDM4E | |
| SCHEMBL1279644 | 0.83 | GAA (0.71) | GAAKMT2AMEN1LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112645852-B | Synthesis method for catalyzing reduction of imine into amine | 赣南医学院 | 2022-06-14 | — | — | CN | disclosed |