Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.69 |
| ▸ | TP53 | P04637 | 4/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | HTT | P42858 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | PKM | P14618 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21550423 | 0.85 | GAA (0.52) | GAATP53LMNAHTTALDH1A1 | |
| SCHEMBL9812983 | 0.85 | GAA (0.62) | GAATP53KMT2ALMNAMEN1 | |
| SCHEMBL4661701 | 0.84 | GAA (0.72) | GAAKMT2ALMNAMEN1HTT | |
| SCHEMBL29660937 | 0.84 | GAA (0.72) | GAAKMT2ALMNAMEN1HTT | |
| SCHEMBL26921059 | 0.84 | GAA (0.68) | GAATP53KMT2ALMNAMEN1 | |
| SCHEMBL5165402 | 0.81 | GAA (0.64) | GAATP53KMT2ALMNAMEN1 | |
| SCHEMBL29540801 | 0.80 | KEAP1 (0.70) | GAAKMT2ALMNAMEN1ALDH1A1 | |
| SCHEMBL30927263 | 0.78 | GAA (0.50) | GAAKMT2ALMNAMEN1ALDH1A1 | |
| SCHEMBL7414750 | 0.76 | KMT2A (0.54) | GAATP53KMT2AMEN1HTT | |
| SCHEMBL10774143 | 0.76 | ALDH1A1 (0.55) | GAATP53KMT2ALMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0223593-B1 | PHENOXYALKYLCARBOXYLIC ACIDS AND ESTERS AND THEIR PREPARATION AND PHARMACEUTICAL FORMULATION | GLAXO GROUP LIMITED (GB) | 1991-08-07 | — | — | EP | disclosed |
| EP-0223593-A2 | Phenoxyalkylcarboxylic acids and esters and their preparation and pharmaceutical formulation | GLAXO GROUP LIMITED (GB) | 1987-05-27 | — | — | EP | disclosed |