Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 1/20 | 0.54 |
| ▸ | GRN | P28799 | 2/20 | 0.42 |
| ▸ | SORT1 | Q99523 | 2/20 | 0.42 |
| ▸ | CTSL | P07711 | 4/20 | 0.42 |
| ▸ | CTSB | P07858 | 4/20 | 0.42 |
| ▸ | CTSK | P43235 | 3/20 | 0.42 |
| ▸ | CTSS | P25774 | 2/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | TDO2 | P48775 | 1/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | MMP12 | P39900 | 1/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.39 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.39 |
| ▸ | ITGAV | P06756 | 1/20 | 0.38 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.38 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.38 |
| ▸ | ITGAL | P20701 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29616587 | 0.89 | TGM2 (0.46) | TGM2CTSLCTSBCTSKCTSS | |
| SCHEMBL1440950 | 0.82 | IDO1 (0.59) | CTSLCTSBCTSKCTSSIDO1 | |
| SCHEMBL6897897 | 0.82 | IDO1 (0.59) | CTSLCTSBCTSKCTSSIDO1 | |
| SCHEMBL1440952 | 0.82 | IDO1 (0.59) | CTSLCTSBCTSKCTSSIDO1 | |
| SCHEMBL25282430 | 0.77 | CTSK (0.65) | CTSLCTSBCTSKCTSSIDO1 | |
| SCHEMBL15649121 | 0.77 | CTSK (0.62) | CTSLCTSBCTSKCTSSIDO1 | |
| SCHEMBL22122405 | 0.77 | CTSK (0.62) | CTSLCTSBCTSKCTSSIDO1 | |
| SCHEMBL25282429 | 0.77 | CTSK (0.65) | CTSLCTSBCTSKCTSSIDO1 | |
| SCHEMBL4622697 | 0.76 | CTSK (0.67) | CTSLCTSBCTSKCTSSIDO1 | |
| SCHEMBL4800376 | 0.76 | CTSK (0.67) | CTSLCTSBCTSKCTSSIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022109363-A1 | NOVEL SPIROPYRROLIDINE DERIVED ANTIVIRAL AGENTS | ENANTA PHARMACEUTICALS, INC. (US) | 2022-05-27 | — | — | WO | disclosed |