Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATXN2 | Q99700 | 6/20 | 0.45 |
| ▸ | CNR2 | P34972 | 3/20 | 0.38 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28736983 | 1.00 | ATXN2 (0.45) | ATXN2CNR2LRRK2PDE10A | |
| SCHEMBL28737011 | 0.92 | ATXN2 (0.47) | ATXN2CNR2LRRK2 | |
| SCHEMBL28737007 | 0.85 | ATXN2 (0.48) | ATXN2CNR2PDE10A | |
| SCHEMBL28737062 | 0.83 | ENPP2 (0.42) | CNR2LRRK2 | |
| SCHEMBL17112461 | 0.77 | ATXN2 (0.57) | ATXN2CNR2PDE10A | |
| SCHEMBL25355431 | 0.77 | FDPS (0.35) | CNR2 | |
| SCHEMBL30454394 | 0.77 | FDPS (0.35) | CNR2 | |
| SCHEMBL4540518 | 0.73 | HCRTR1 (0.42) | CNR2 | |
| SCHEMBL28736982 | 0.73 | ATXN2 (0.45) | ATXN2CNR2LRRK2 | |
| SCHEMBL28820933 | 0.72 | CNR2 (0.44) | CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110204550-B | Bicyclic compounds as Autotaxin (ATX) and lysophosphatidic acid (LPA) production inhibitors | 豪夫迈·罗氏有限公司 | 2022-05-17 | — | — | CN | disclosed |