SCHEMBL29664378

SCHEMBL29664378

O=c1c(-c2c(-c3ccc(O)c(O)c3)oc3cc(O)cc(O)c3c2=O)c(-c2ccc(O)c(O)c2)oc2cc(O)cc(O)c12

nearest known ligand 0.79

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLH Q9Y253 10/20 0.79
MEN1 O00255 9/20 0.79
KMT2A Q03164 9/20 0.79
KDM4E B2RXH2 8/20 0.79
HSD17B10 Q99714 7/20 0.79
RECQL P46063 7/20 0.79
CYP3A4 P08684 7/20 0.79
MAPT P10636 7/20 0.79
POLB P06746 6/20 0.79
CYP1A2 P05177 5/20 0.79
CYP2C9 P11712 5/20 0.79
ALOX15 P16050 5/20 0.79
HIF1A Q16665 5/20 0.79
BLM P54132 5/20 0.79
APP P05067 5/20 0.79
AKR1B1 P15121 5/20 0.79
IPMK Q8NFU5 5/20 0.79
TDP1 Q9NUW8 5/20 0.79
IP6K2 Q9UHH9 5/20 0.79
GAA P10253 4/20 0.79

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Quercetin SCHEMBL28612593 0.90 MEN1 (0.97) POLHMEN1KMT2AKDM4EHSD17B10
Quercetin SCHEMBL29351036 0.88 MEN1 (1.00) POLHMEN1KMT2AKDM4EHSD17B10
Quercetin SCHEMBL29723041 0.88 MEN1 (1.00) POLHMEN1KMT2AKDM4EHSD17B10
Quercetin SCHEMBL118425 0.88 MEN1 (1.00) POLHMEN1KMT2AKDM4EHSD17B10
Quercetin SCHEMBL19723 0.88 MEN1 (1.00) POLHMEN1KMT2AKDM4EHSD17B10
Quercetin SCHEMBL29353785 0.88 MEN1 (1.00) POLHMEN1KMT2AKDM4EHSD17B10
Quercetin SCHEMBL17629824 0.88 MEN1 (1.00) POLHMEN1KMT2AKDM4EHSD17B10
Quercetin SCHEMBL31507620 0.88 MEN1 (1.00) POLHMEN1KMT2AKDM4EHSD17B10
SCHEMBL2565483 0.88 CYP3A4 (0.78) POLHMEN1KMT2AKDM4EHSD17B10
SCHEMBL30684642 0.88 CYP3A4 (0.78) POLHMEN1KMT2AKDM4EHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240122894-A1 METHODS TO SYNTHESIZE FLAVONOID DIMERS AND OLIGOMERS AND THE USE THEREOF NATIONAL UNIVERSITY OF SINGAPORE (SG) 2024-04-18 US disclosed
EP-4259614-A1 METHODS TO SYNTHESIZE FLAVONOID DIMERS AND OLIGOMERS AND THE USE THEREOF National University of Singapore (SG) 2023-10-18 EP disclosed
WO-2022124994-A1 METHODS TO SYNTHESIZE FLAVONOID DIMERS AND OLIGOMERS AND THE USE THEREOF NATIONAL UNIVERSITY OF SINGAPORE (SG) 2022-06-16 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240122894-A1 METHODS TO SYNTHESIZE FLAVONOID DIMERS AND OLIGOMERS AND THE USE THEREOF ERG28, MGAM, CTRB2 POLH 856/4885MEN1 1594/4885KMT2A 4081/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.