Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | TMIGD3 | P0DMS9 | 2/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
| ▸ | AURKA | O14965 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29664232 | 0.73 | AURKA (0.53) | TMIGD3ADORA3AURKA | |
| SCHEMBL24864096 | 0.72 | CYP1A2 (0.40) | HTR2CL3MBTL1AURKA | |
| SCHEMBL3804294 | 0.68 | GPR119 (0.38) | — | |
| SCHEMBL29664463 | 0.66 | AURKA (0.64) | AURKA | |
| SCHEMBL2273731 | 0.65 | HTR2C (0.47) | HTR2CL3MBTL1AURKA | |
| SCHEMBL103894 | 0.65 | HTR2C (0.53) | HTR2CL3MBTL1AURKA | |
| SCHEMBL29893796 | 0.64 | ADORA2A (0.45) | HTR2CL3MBTL1 | |
| SCHEMBL15956956 | 0.63 | AURKA (0.50) | HTR2CAURKA | |
| SCHEMBL2221438 | 0.63 | AURKA (0.60) | HTR2CAURKA | |
| SCHEMBL19865160 | 0.62 | L3MBTL1 (0.53) | HTR2CL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113480543-B | 2,6, 8-polysubstituted imidazo [1,2-a ] pyrazine and synthetic method and application thereof | 无锡市第二人民医院 | 2022-05-17 | — | — | CN | disclosed |