Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.70 |
| ▸ | BLVRB | P30043 | 1/20 | 0.70 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.70 |
| ▸ | ACMSD | Q8TDX5 | 4/20 | 0.67 |
| ▸ | NPC1 | O15118 | 12/20 | 0.66 |
| ▸ | RAB9A | P51151 | 12/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.62 |
| ▸ | MEN1 | O00255 | 4/20 | 0.62 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.62 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.62 |
| ▸ | RELA | Q04206 | 3/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.62 |
| ▸ | PKM | P14618 | 2/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | CHUK | O15111 | 1/20 | 0.51 |
| ▸ | CASP3 | P42574 | 1/20 | 0.51 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL384904 | 1.00 | MAOA (0.70) | MAOABLVRBHDAC6ACMSDNPC1 | |
| SCHEMBL385108 | 0.88 | MAOA (0.66) | MAOABLVRBHDAC6ACMSDNPC1 | |
| SCHEMBL385293 | 0.85 | NPC1 (0.73) | MAOABLVRBHDAC6ACMSDNPC1 | |
| SCHEMBL12171151 | 0.83 | NPC1 (0.78) | MAOABLVRBHDAC6NPC1RAB9A | |
| Ataluren SCHEMBL29365205 | 0.82 | MAOA (1.00) | MAOABLVRBHDAC6NPC1RAB9A | |
| Ataluren SCHEMBL29361641 | 0.82 | MAOA (1.00) | MAOABLVRBHDAC6NPC1RAB9A | |
| Ataluren SCHEMBL60614 | 0.82 | MAOA (1.00) | MAOABLVRBHDAC6NPC1RAB9A | |
| Ataluren SCHEMBL29360108 | 0.82 | MAOA (1.00) | MAOABLVRBHDAC6NPC1RAB9A | |
| SCHEMBL387630 | 0.81 | NPC1 (0.67) | MAOABLVRBHDAC6ACMSDNPC1 | |
| Ataluren SCHEMBL59167 | 0.81 | MAOA (0.97) | MAOABLVRBHDAC6NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240059656-A1 | A TAUTOMERIC LIGAND ENABLES BIOMIMETIC C-H HYDROXYLATION WITH MOLECULAR OXYGEN | THE SCRIPPS RESEARCH INSTITUTE | 2024-02-22 | — | — | US | disclosed |
| WO-2022125736-A1 | A TAUTOMERIC LIGAND ENABLES BIOMIMETIC C-H HYDROXYLATION WITH MOLECULAR OXYGEN | THE SCRIPPS RESEARCH INSTITUTE (US) | 2022-06-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240059656-A1 | A TAUTOMERIC LIGAND ENABLES BIOMIMETIC C-H HYDROXYLATION WITH MOLECULAR OXYGEN | PAH, OGDH, DOHH | MAOA 42/4885BLVRB 213/4885HDAC6 2493/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.