Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 5/20 | 0.52 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | GLS | O94925 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | DRD1 | P21728 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | CASR | P41180 | 1/20 | 0.46 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23216480 | 1.00 | MTNR1A (0.52) | MTNR1AMTNR1BTDP1L3MBTL1LMNA | |
| SCHEMBL28269689 | 0.89 | MTNR1A (0.51) | MTNR1AMTNR1BTDP1L3MBTL1LMNA | |
| SCHEMBL28269690 | 0.89 | MTNR1A (0.51) | MTNR1AMTNR1BTDP1L3MBTL1LMNA | |
| SCHEMBL7980726 | 0.84 | KMT2A (0.55) | LMNA | |
| SCHEMBL7042372 | 0.83 | MTNR1A (0.62) | MTNR1AMTNR1BKDM4ECASR | |
| SCHEMBL29664805 | 0.83 | MTNR1A (0.44) | MTNR1AMTNR1BL3MBTL1GLSKDM4E | |
| SCHEMBL23216797 | 0.83 | MTNR1A (0.44) | MTNR1AMTNR1BL3MBTL1GLSKDM4E | |
| SCHEMBL28577126 | 0.82 | KDM4E (0.60) | MTNR1AMTNR1BTDP1L3MBTL1GLS | |
| SCHEMBL11436413 | 0.81 | L3MBTL1 (0.62) | MTNR1AMTNR1BTDP1L3MBTL1LMNA | |
| SCHEMBL6301200 | 0.81 | MTNR1A (0.67) | MTNR1AMTNR1BTDP1L3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114729044-A | Muscarinic acetylcholine M1Receptor antagonists | 帕珀莱恩医疗公司 | 2022-07-08 | — | — | CN | disclosed |