Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 5/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | GLS | O94925 | 2/20 | 0.43 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.41 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | DRD1 | P21728 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | CASR | P41180 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23216797 | 1.00 | MTNR1A (0.44) | MTNR1AMTNR1BL3MBTL1GLSKCNQ2 | |
| SCHEMBL26094197 | 0.85 | CTSB (0.38) | CASR | |
| SCHEMBL29664636 | 0.83 | MTNR1A (0.52) | MTNR1AMTNR1BL3MBTL1GLSAOC3 | |
| SCHEMBL23216480 | 0.83 | MTNR1A (0.52) | MTNR1AMTNR1BL3MBTL1GLSAOC3 | |
| SCHEMBL31724365 | 0.81 | L3MBTL1 (0.47) | MTNR1AMTNR1BL3MBTL1KCNQ2AOC3 | |
| SCHEMBL25289023 | 0.79 | AOC3 (0.44) | MTNR1AMTNR1BL3MBTL1GLSKCNQ2 | |
| SCHEMBL28577126 | 0.77 | KDM4E (0.60) | MTNR1AMTNR1BL3MBTL1GLSKCNQ2 | |
| SCHEMBL21656313 | 0.77 | L3MBTL1 (0.50) | MTNR1AMTNR1BL3MBTL1GLSKCNQ2 | |
| SCHEMBL30932899 | 0.76 | L3MBTL1 (0.55) | MTNR1AMTNR1BL3MBTL1GLSAOC3 | |
| SCHEMBL21510039 | 0.76 | ALDH1A1 (0.49) | MTNR1AMTNR1BL3MBTL1GLS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114729044-A | Muscarinic acetylcholine M1Receptor antagonists | 帕珀莱恩医疗公司 | 2022-07-08 | — | — | CN | disclosed |