SCHEMBL29664773

SCHEMBL29664773

COc1ccc2c(c1)C(C)NCC2

nearest known ligand 0.65

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
HTR2B P41595 2/20 0.65
HTR2C P28335 2/20 0.65
HTR2A P28223 1/20 0.65
MAOA P21397 8/20 0.61
TSHR P16473 2/20 0.61
ALDH1A1 P00352 2/20 0.55
HSD17B10 Q99714 2/20 0.55
CYP2D6 P10635 1/20 0.55
MAPT P10636 2/20 0.54
KDM4E B2RXH2 2/20 0.54
PSMD14 O00487 1/20 0.54
POLB P06746 1/20 0.54
GAA P10253 1/20 0.54
DRD2 P14416 2/20 0.51
CYP2C9 P11712 1/20 0.51
DRD3 P35462 1/20 0.51
HIF1A Q16665 1/20 0.51
DRD4 P21917 1/20 0.51
GID4 Q8IVV7 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1010321 1.00 HTR2B (0.65) HTR2BHTR2CHTR2AMAOATSHR
SCHEMBL21470620 1.00 HTR2B (0.65) HTR2BHTR2CHTR2AMAOATSHR
SCHEMBL1010205 0.87 HTR2C (0.63) HTR2BHTR2CHTR2AMAOATSHR
SCHEMBL30932908 0.87 HTR2C (0.63) HTR2BHTR2CHTR2AMAOATSHR
Hydrochloric Acid SCHEMBL9433620 0.85 MAOA (0.62) HTR2BHTR2CHTR2AMAOATSHR
SCHEMBL19752839 0.82 HTR2C (0.59) HTR2BHTR2CHTR2AMAOAALDH1A1
SCHEMBL30751025 0.81 MAOA (0.48) HTR2BHTR2CHTR2AMAOATSHR
SCHEMBL32684319 0.81 HTR2C (0.57) HTR2BHTR2CHTR2AMAOAALDH1A1
SCHEMBL28623600 0.80 HTR2C (0.56) HTR2BHTR2CHTR2AMAOAALDH1A1
SCHEMBL30878551 0.79 MAOA (0.46) HTR2BHTR2CHTR2AMAOATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4547250-A1 METHODS AND COMPOSITIONS RELATING TO CONTROLLING PSYCHEDELIC EFFECTS WITH SEROTONIN RECEPTOR MODULATORS Terran Biosciences Inc. (US) 2025-05-07 EP claimed
US-20240197681-A1 METHODS AND COMPOSITIONS RELATING TO PSYCHEDELICS AND SEROTONIN RECEPTOR MODULATORS NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2024-06-20 US claimed
WO-2024006984-A1 METHODS AND COMPOSITIONS RELATING TO CONTROLLING PSYCHEDELIC EFFECTS WITH SEROTONIN RECEPTOR MODULATORS TERRAN BIOSCIENCES INC. (US) 2024-01-04 WO claimed
CN-115594669-B Parallel ring derivative and preparation method and medical application thereof 深圳信立泰药业股份有限公司 2024-11-05 CN disclosed
CN-115594669-A Fused ring derivative and preparation method and medical application thereof 深圳信立泰药业股份有限公司(CN) 2023-01-13 CN disclosed
CN-114729044-A Muscarinic acetylcholine M1Receptor antagonists 帕珀莱恩医疗公司 2022-07-08 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240197681-A1 METHODS AND COMPOSITIONS RELATING TO PSYCHEDELICS AND SEROTONIN RECEPTOR MODULATORS HTR1A, HTR2A, HTR3A HTR2B 11/4885HTR2C 5/4885HTR2A 2/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.