SCHEMBL29666271

SCHEMBL29666271

CC1(C)CN=Cc2ccccc21

nearest known ligand 0.38

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 1/20 0.31
NOTUM Q6P988 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL52343 1.00 HTR2A (0.31) HTR2ANOTUM
SCHEMBL24124845 0.80
SCHEMBL29360641 0.79 SIGMAR1 (0.37)
SCHEMBL14817223 0.75
SCHEMBL30024117 0.75
SCHEMBL29516288 0.75
Hydrochloric Acid SCHEMBL29791533 0.73
SCHEMBL30271241 0.73 KDM4E (0.32)
SCHEMBL30090202 0.72 ADORA3 (0.31)
SCHEMBL30498729 0.72 NOTUM (0.33) NOTUM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114516856-B Dihydro-isoquinolinone and isoindolinone derivatives and application thereof 安徽中科拓苒药物科学研究有限公司 2025-05-23 CN disclosed
WO-2022105526-A1 DIHYDROISOQUINOLINONE AND ISOINDOLINONE DERIVATIVES AND USES THEREOF 中国科学院合肥物质科学研究院 2022-05-27 WO disclosed
CN-114516856-A Dihydroisoquinolinone and isoindolinone derivatives and uses thereof 中国科学院合肥物质科学研究院 2022-05-20 CN disclosed