Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHKA | P35790 | 4/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | DPP4 | P27487 | 2/20 | 0.56 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.56 |
| ▸ | PDE2A | O00408 | 1/20 | 0.49 |
| ▸ | HTR2B | P41595 | 1/20 | 0.47 |
| ▸ | JAK2 | O60674 | 1/20 | 0.45 |
| ▸ | JAK1 | P23458 | 1/20 | 0.45 |
| ▸ | JAK3 | P52333 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.41 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.41 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.41 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20238481 | 1.00 | CHKA (0.62) | CHKAALDH1A1HTTDPP4DPP8 | |
| SCHEMBL1935654 | 0.97 | ALDH1A1 (0.63) | CHKAALDH1A1HTTDPP4DPP8 | |
| SCHEMBL4710474 | 0.86 | DPP4 (0.50) | CHKAALDH1A1HTTDPP4DPP8 | |
| SCHEMBL4712397 | 0.86 | CHKA (0.55) | CHKAALDH1A1HTTDPP4DPP8 | |
| SCHEMBL29668920 | 0.84 | CHKA (0.50) | CHKADPP4DPP8HRH3 | |
| SCHEMBL20238579 | 0.84 | CHKA (0.50) | CHKADPP4DPP8HRH3 | |
| SCHEMBL22322038 | 0.84 | ALDH1A1 (0.63) | CHKAALDH1A1HTTDPP4DPP8 | |
| SCHEMBL27822767 | 0.84 | DPP4 (0.57) | CHKAALDH1A1HTTDPP4DPP8 | |
| SCHEMBL4789120 | 0.82 | DPP4 (0.57) | CHKAALDH1A1HTTDPP4DPP8 | |
| SCHEMBL27545359 | 0.81 | CHKA (0.47) | CHKAALDH1A1HTTDPP4DPP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110325531-B | Benzenesulfonamides and their use as therapeutic agents | 泽农医药公司 | 2022-05-27 | — | — | CN | disclosed |