SCHEMBL29670146

SCHEMBL29670146

CC(C)c1ccc(P(C(C)(C)C)C(C)(C)C)cc1.[Pd]

nearest known ligand 0.37

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TYR P14679 2/20 0.37
CYP2C9 P11712 3/20 0.35
CYP2D6 P10635 1/20 0.35
HIF1A Q16665 1/20 0.35
HTT P42858 1/20 0.34
IDO1 P14902 2/20 0.33
ADRB2 P07550 1/20 0.33
MGLL Q99685 1/20 0.32
LMNA P02545 1/20 0.31
PTPN5 P54829 1/20 0.31
KDM4E B2RXH2 1/20 0.31
MAPK1 P28482 1/20 0.31
HPGD P15428 1/20 0.31
TRPA1 O75762 1/20 0.30
PTGS1 P23219 1/20 0.30
CACNA1C Q13936 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16694097 0.98 TYR (0.38) TYRCYP2C9CYP2D6HIF1AHTT
SCHEMBL2557952 0.80
SCHEMBL29670088 0.77 GABRA1 (0.30)
SCHEMBL2550429 0.75 LMNA (0.44) CYP2C9CYP2D6HIF1AIDO1ADRB2
SCHEMBL29670251 0.75 HDAC4 (0.39) TYRHTTLMNAPTPN5KDM4E
SCHEMBL16694101 0.74 GABRA1 (0.31) CYP2D6
SCHEMBL16866207 0.73 MAPT (0.42) HIF1AKDM4EMAPK1HPGD
SCHEMBL16694196 0.72 HDAC4 (0.40) TYRHIF1AHTTLMNAPTPN5
SCHEMBL29590068 0.72 HDAC4 (0.40) TYRHIF1AHTTLMNAPTPN5
SCHEMBL3769642 0.72 TYR (0.44) TYRCYP2C9CYP2D6HIF1AHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022114117-A1 PALLADIUM COMPLEX, COUPLING REACTION CATAYLST, AND METHOD FOR PRODUCING AROMATIC COMPOUND エヌ・イーケムキャット株式会社 2022-06-02 WO disclosed