Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.46 |
| ▸ | TOP2A | P11388 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | MET | P08581 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.40 |
| ▸ | FEN1 | P39748 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26842911 | 0.84 | CYP19A1 (0.49) | TOP2ANPC1RAB9AMEN1KMT2A | |
| SCHEMBL30071507 | 0.84 | CYP3A4 (0.49) | TOP2ANPC1RAB9AMEN1KMT2A | |
| SCHEMBL31510780 | 0.77 | CYP19A1 (0.55) | CA1CA2ENPP2TOP2ANPC1 | |
| SCHEMBL17898982 | 0.75 | TOP2A (0.42) | TOP2ANPC1RAB9AMEN1KMT2A | |
| SCHEMBL29670353 | 0.75 | GAA (0.51) | CA1CA2ENPP2NPC1RAB9A | |
| SCHEMBL31510674 | 0.75 | MEN1 (0.72) | NPC1RAB9AMEN1KMT2AL3MBTL1 | |
| SCHEMBL24470004 | 0.74 | CA1 (0.44) | CA1CA2ENPP2CYP1A2CYP3A4 | |
| SCHEMBL17898983 | 0.73 | MMP13 (0.46) | TOP2AMEN1KMT2AAKR1C3CYP1A2 | |
| SCHEMBL17898981 | 0.71 | TOP2A (0.43) | TOP2ANPC1RAB9AMEN1KMT2A | |
| SCHEMBL24570328 | 0.71 | RAB9A (0.53) | NPC1RAB9AAKR1C3CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022115384-A1 | TRICYCLIC COMPOUNDS | ALIGOS THERAPEUTICS, INC. (US) | 2022-06-02 | — | — | WO | disclosed |