SCHEMBL29670282

SCHEMBL29670282

Nc1ccc2cc[nH]c2c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AHR P35869 4/20 0.56
CMA1 P23946 1/20 0.56
TYR P14679 1/20 0.56
HTR6 P50406 1/20 0.51
ENPP2 Q13822 2/20 0.50
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
POLB P06746 1/20 0.50
MAPK1 P28482 1/20 0.50
CYP2A6 P11509 1/20 0.50
EGFR P00533 1/20 0.49
KDM4E B2RXH2 3/20 0.48
ALDH1A1 P00352 2/20 0.48
HSD17B10 Q99714 2/20 0.48
HPGD P15428 1/20 0.48
MAPT P10636 2/20 0.47
PKM P14618 1/20 0.47
HTT P42858 1/20 0.47
GPR84 Q9NQS5 1/20 0.46
TRPA1 O75762 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL94619 1.00 AHR (0.56) AHRCMA1TYRHTR6ENPP2
Hydrochloric Acid SCHEMBL7359009 0.98 AHR (0.54) AHRCMA1TYRHTR6ENPP2
Iodide SCHEMBL29022371 0.98 AHR (0.54) AHRCMA1TYRHTR6ENPP2
Bromide SCHEMBL27451953 0.98 AHR (0.54) AHRCMA1TYRHTR6ENPP2
Hydrochloric Acid SCHEMBL31197107 0.98 AHR (0.54) AHRCMA1TYRHTR6ENPP2
Propionic Acid SCHEMBL6598879 0.82 ENPP2 (0.51) AHRCMA1TYRHTR6ENPP2
SCHEMBL130519 0.81 AHR (0.56) AHRMEN1KMT2ACYP2A6EGFR
SCHEMBL29560117 0.81 AHR (0.56) AHRMEN1KMT2ACYP2A6EGFR
Hydrochloric Acid SCHEMBL3325397 0.79 AHR (0.54) AHRMEN1KMT2ACYP2A6EGFR
Iodide SCHEMBL7361153 0.79 AHR (0.54) AHRMEN1KMT2ACYP2A6EGFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4676474-A2 SYMMETRIC AMINOINDOLE-LINKED TRIAZINE FOR A DUAL EFFECT ON ALPHA-SYNUCLEIN AND TAU ISOFORM 2N4R FIBRILLIZATION Purdue Research Foundation (US) 2026-01-14 EP claimed
WO-2024206067-A2 SYMMETRIC AMINOINDOLE-LINKED TRIAZINE FOR A DUAL EFFECT ON ALPHA-SYNUCLEIN AND TAU ISOFORM 2N4R FIBRILLIZATION PURDUE RESEARCH FOUNDATION (US) 2024-10-03 WO claimed
EP-3416948-B1 INDACENE BEARING SULFONYLUREAS AS ANTI-INFLAMMATORY AGENTS UNIV QUEENSLAND (AU) 2024-07-24 EP claimed
EP-4676474-A2 SYMMETRIC AMINOINDOLE-LINKED TRIAZINE FOR A DUAL EFFECT ON ALPHA-SYNUCLEIN AND TAU ISOFORM 2N4R FIBRILLIZATION Purdue Research Foundation (US) 2026-01-14 EP disclosed
US-12486300-B2 Mithramycin oxime derivatives having increased selectivity and anti-cancer activity UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) 2025-12-02 US disclosed
WO-2024206067-A3 SYMMETRIC AMINOINDOLE-LINKED TRIAZINE FOR A DUAL EFFECT ON ALPHA-SYNUCLEIN AND TAU ISOFORM 2N4R FIBRILLIZATION PURDUE RESEARCH FOUNDATION (US) 2024-11-07 WO disclosed
WO-2024206067-A2 SYMMETRIC AMINOINDOLE-LINKED TRIAZINE FOR A DUAL EFFECT ON ALPHA-SYNUCLEIN AND TAU ISOFORM 2N4R FIBRILLIZATION PURDUE RESEARCH FOUNDATION (US) 2024-10-03 WO disclosed
EP-2277597-B2 Reductive colour removal HENKEL AG & CO KGAA (DE) 2024-06-26 EP disclosed
WO-2024081692-A1 MITHRAMYCIN OXIME DERIVATIVES HAVING INCREASED SELECTIVITY AND ANTI-CANCER ACTIVITY UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) 2024-04-18 WO disclosed
EP-4334303-A1 COMPOUNDS FOR INHIBITING OR DEGRADING ITK, COMPOSITIONS, COMPRISING THE SAME METHODS OF THEIR MAKING AND METHODS OF THEIR USE Nurix Therapeutics, Inc. (US) 2024-03-13 EP disclosed
EP-4334302-A1 COMPOUNDS FOR INHIBITING OR DEGRADING TARGET PROTEINS, COMPOSITIONS, COMPRISING THE SAME, METHODS OF THEIR MAKING, AND METHODS OF THEIR USE Nurix Therapeutics, Inc. (US) 2024-03-13 EP disclosed
CN-117136184-A Aminopyrimidine compounds and methods of use thereof 泰拉生物科学公司 2023-11-28 CN disclosed
US-20230132854-A1 MITHRAMYCIN OXIME DERIVATIVES HAVING INCREASED SELECTIVITY AND ANTI-CANCER ACTIVITY UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION 2023-05-04 US disclosed
US-20230047905-A1 COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY NOVARTIS PHARMA AG (CH) 2023-02-16 US disclosed
EP-4103278-A1 SMALL MOLECULE STING ANTAGONISTS Curadev Pharma Pvt. Ltd. (IN) 2022-12-21 EP disclosed
WO-2022235715-A1 COMPOUNDS FOR INHIBITING OR DEGRADING ITK, COMPOSITIONS, COMPRISING THE SAME METHODS OF THEIR MAKING AND METHODS OF THEIR USE NURIX THERAPEUTICS, INC. (US) 2022-11-10 WO disclosed
WO-2022235698-A1 COMPOUNDS FOR INHIBITING OR DEGRADING TARGET PROTEINS, COMPOSITIONS, COMPRISING THE SAME, METHODS OF THEIR MAKING, AND METHODS OF THEIR USE NURIX THERAPEUTICS, INC. (US) 2022-11-10 WO disclosed
US-11466045-B2 Mithramycin oxime derivatives having increased selectivity and anti-cancer activity UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) 2022-10-11 US disclosed
EP-3998059-A9 MILD PREPARATIONS AS CLEANING OR CARE COMPOSITIONS FOR REMOVING CARBOHYDRATES OR STAINS Perfect Ideas GmbH (CH) 2022-09-28 EP disclosed
EP-3998059-A1 MILD PREPARATIONS AS CLEANING OR CARE COMPOSITIONS FOR REMOVING CARBOHYDRATES OR STAINS Perfect Ideas GmbH (CH) 2022-05-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12486300-B2 Mithramycin oxime derivatives having increased selectivity and anti-cancer activity TFAM, HSPE1, PRDX3 AHR 2330/4885CMA1 4438/4885TYR 1018/4885
US-11466045-B2 Mithramycin oxime derivatives having increased selectivity and anti-cancer activity HSPE1, TFAM, HMOX1 AHR 1075/4885CMA1 3875/4885TYR 714/4885
US-20230132854-A1 MITHRAMYCIN OXIME DERIVATIVES HAVING INCREASED SELECTIVITY AND ANTI-CANCER ACTIVITY TFAM, HSPE1, PRDX3 AHR 2330/4885CMA1 4438/4885TYR 1018/4885
US-20230047905-A1 COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY STING1, CGAS, IRF3 AHR 2635/4885CMA1 596/4885TYR 1382/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.