SCHEMBL29670293

SCHEMBL29670293

CC(C)[C@H](NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)N(C)[C@@H](CCC(=O)NC(c1ccccc1)(c1ccccc1)c1ccccc1)C(=O)O

nearest known ligand 0.44

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CASP3 P42574 4/20 0.44
MDM4 O15151 2/20 0.41
TP53 P04637 2/20 0.41
TLR2 O60603 2/20 0.40
PIN1 Q13526 1/20 0.38
KMT2A Q03164 2/20 0.38
MDM2 Q00987 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29670299 0.88 CASP3 (0.51) CASP3MDM4TP53TLR2KMT2A
SCHEMBL30506093 0.85 KMT2A (0.39) CASP3MDM4TP53TLR2KMT2A
SCHEMBL18725617 0.85 KMT2A (0.39) CASP3MDM4TP53TLR2KMT2A
SCHEMBL18725616 0.85 KMT2A (0.39) CASP3MDM4TP53TLR2KMT2A
SCHEMBL29670240 0.85 CASP3 (0.45) CASP3MDM4TP53TLR2KMT2A
SCHEMBL29670207 0.81 CASP3 (0.49) CASP3MDM4TP53PIN1KMT2A
SCHEMBL29670446 0.81 CASP3 (0.47) CASP3MDM4TP53PIN1KMT2A
SCHEMBL31217659 0.80 TLR2 (0.55) CASP3MDM4TP53TLR2KMT2A
SCHEMBL13227676 0.80 TLR2 (0.55) CASP3MDM4TP53TLR2KMT2A
SCHEMBL1755686 0.80 TLR2 (0.55) CASP3MDM4TP53TLR2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12240871-B2 Method for producing peptide compound NISSAN CHEMICAL CORPORATION (JP) 2025-03-04 US disclosed
US-20220153777-A1 METHOD FOR PRODUCING PEPTIDE COMPOUND NISSAN CHEMICAL CORPORATION (JP) 2022-05-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12240871-B2 Method for producing peptide compound NGLY1, NPPA, NPEPPS CASP3 1076/4885MDM4 2239/4885TP53 2675/4885
US-20220153777-A1 METHOD FOR PRODUCING PEPTIDE COMPOUND NGLY1, NPPA, NPEPPS CASP3 1076/4885MDM4 2239/4885TP53 2675/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.