SCHEMBL29670308

SCHEMBL29670308

CC(C)(C)P(c1ccc(F)cc1)C(C)(C)C.[Pd]

nearest known ligand 0.38

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.38
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA7 P43166 1/20 0.32
CA9 Q16790 1/20 0.32
MEN1 O00255 1/20 0.31
NPC1 O15118 1/20 0.31
MAPT P10636 1/20 0.31
XBP1 P17861 1/20 0.31
MAPK1 P28482 1/20 0.31
HTT P42858 1/20 0.31
RAB9A P51151 1/20 0.31
KMT2A Q03164 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
ALDH1A1 P00352 1/20 0.31
NFE2L2 Q16236 1/20 0.30
KCNH2 Q12809 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2550793 0.97 ACHE (0.39) ACHECA1CA2CA7CA9
SCHEMBL17239672 0.89 ACHE (0.33) ACHE
SCHEMBL20591115 0.87 ACHE (0.32) ACHE
SCHEMBL20591116 0.85 ACHE (0.31) ACHEMEN1MAPTHTTKMT2A
SCHEMBL2557952 0.84
SCHEMBL18963569 0.81 KDM4E (0.34) ACHEALDH1A1KCNH2
SCHEMBL14811633 0.76 ALDH1A1 (0.39) ALDH1A1
SCHEMBL30093072 0.76 KIF11 (0.32)
SCHEMBL29670169 0.75 CA12 (0.32) CA1CA9
SCHEMBL29670197 0.75 TSHR (0.46) ACHECA1CA2CA9NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022114117-A1 PALLADIUM COMPLEX, COUPLING REACTION CATAYLST, AND METHOD FOR PRODUCING AROMATIC COMPOUND エヌ・イーケムキャット株式会社 2022-06-02 WO disclosed