Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
| ▸ | KMO | O15229 | 2/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | GABRP | O00591 | 1/20 | 0.40 |
| ▸ | GABRD | O14764 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.40 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.40 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.40 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.40 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.40 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.40 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.40 |
| ▸ | GABRE | P78334 | 1/20 | 0.40 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.40 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.40 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.40 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16517647 | 1.00 | ABL1 (0.42) | ABL1KMOCASP1GABRPGABRD | |
| SCHEMBL19944955 | 0.86 | ABL1 (0.41) | ABL1KMOCASP1GABRPGABRD | |
| SCHEMBL16544987 | 0.85 | KMO (0.38) | ABL1KMOCASP1GABRPGABRD | |
| SCHEMBL31309760 | 0.84 | SMN1; SMN2 (0.45) | ADORA2AADORA1KCNH2 | |
| SCHEMBL16533475 | 0.84 | SMN1; SMN2 (0.45) | ADORA2AADORA1KCNH2 | |
| SCHEMBL16533606 | 0.83 | KMO (0.37) | ABL1KMOCASP1GABRPGABRD | |
| SCHEMBL16544988 | 0.82 | CYP11B2 (0.39) | ABL1KMOCASP1CNR1CNR2 | |
| SCHEMBL16545247 | 0.82 | TRPV3 (0.42) | ABL1KMOCASP1CNR1CNR2 | |
| SCHEMBL16533573 | 0.81 | ABL1 (0.46) | ABL1KMOCASP1CNR1CNR2 | |
| SCHEMBL16533657 | 0.80 | TRPV3 (0.41) | ABL1KMOCASP1GABRPGABRD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114716426-A | Antiviral compounds | 詹森生物制药有限公司 | 2022-07-08 | — | — | CN | disclosed |
| CN-105636936-B | Antiviral compounds | 詹森生物制药有限公司 | 2022-04-05 | — | — | CN | disclosed |