Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | TP53 | P04637 | 3/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28705641 | 1.00 | MAPT (0.52) | MAPTTP53THRBGAAKMT2A | |
| SCHEMBL28715922 | 0.91 | MAPT (0.57) | MAPTTP53THRBGAAKMT2A | |
| SCHEMBL29670966 | 0.91 | MAPT (0.57) | MAPTTP53THRBGAAKMT2A | |
| SCHEMBL28719380 | 0.85 | MAPT (0.55) | MAPTTP53THRBKMT2ATSHR | |
| SCHEMBL29670976 | 0.85 | MAPT (0.55) | MAPTTP53THRBKMT2ATSHR | |
| SCHEMBL29670970 | 0.85 | KMT2A (0.51) | MAPTTP53THRBGAAKMT2A | |
| SCHEMBL28718270 | 0.85 | KMT2A (0.51) | MAPTTP53THRBGAAKMT2A | |
| SCHEMBL28937215 | 0.83 | MMP2 (0.52) | MAPTTHRBGAAKDM4EALDH1A1 | |
| SCHEMBL29670974 | 0.83 | MMP2 (0.52) | MAPTTHRBGAAKDM4EALDH1A1 | |
| SCHEMBL28719007 | 0.82 | MMP2 (0.46) | MAPTTP53THRBKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114276303-B | Ureido compounds or pharmaceutically acceptable salts thereof, and preparation method and application thereof | 河南大学 | 2023-09-22 | — | — | CN | disclosed |
| CN-114276303-A | Ureido compound or its medicinal salt and its preparing process and application | 河南大学 | 2022-04-05 | — | — | CN | disclosed |