Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 3/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | LCK | P06239 | 1/20 | 0.46 |
| ▸ | MET | P08581 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.43 |
| ▸ | MMP1 | P03956 | 2/20 | 0.43 |
| ▸ | MMP9 | P14780 | 2/20 | 0.43 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | GPR6 | P46095 | 2/20 | 0.40 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28937215 | 1.00 | MMP2 (0.52) | MMP2HSD17B10KDM4EALDH1A1GAA | |
| SCHEMBL28719369 | 0.88 | MMP2 (0.46) | MMP2HSD17B10KDM4EALDH1A1GAA | |
| SCHEMBL29670969 | 0.88 | MMP2 (0.46) | MMP2HSD17B10KDM4EALDH1A1GAA | |
| SCHEMBL29670976 | 0.85 | MAPT (0.55) | MMP2HSD17B10KDM4EALDH1A1MAPT | |
| SCHEMBL28719380 | 0.85 | MAPT (0.55) | MMP2HSD17B10KDM4EALDH1A1MAPT | |
| SCHEMBL29670975 | 0.84 | MMP2 (0.46) | MMP2HSD17B10KDM4EALDH1A1MAPT | |
| SCHEMBL28719007 | 0.84 | MMP2 (0.46) | MMP2HSD17B10KDM4EALDH1A1MAPT | |
| SCHEMBL29670957 | 0.83 | MAPT (0.52) | KDM4EALDH1A1GAAMAPTSMN1; SMN2 | |
| SCHEMBL28705641 | 0.83 | MAPT (0.52) | KDM4EALDH1A1GAAMAPTSMN1; SMN2 | |
| SCHEMBL29670964 | 0.82 | MAPT (0.48) | MMP2KDM4EALDH1A1MAPTALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114276303-B | Ureido compounds or pharmaceutically acceptable salts thereof, and preparation method and application thereof | 河南大学 | 2023-09-22 | — | — | CN | disclosed |
| CN-114276303-A | Ureido compound or its medicinal salt and its preparing process and application | 河南大学 | 2022-04-05 | — | — | CN | disclosed |