Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | LCK | P06239 | 1/20 | 0.49 |
| ▸ | MET | P08581 | 1/20 | 0.49 |
| ▸ | KDR | P35968 | 1/20 | 0.49 |
| ▸ | TEK | Q02763 | 1/20 | 0.49 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.48 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | AVPR1A | P37288 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28718270 | 1.00 | KMT2A (0.51) | KMT2AMEN1GAALCKMET | |
| SCHEMBL28715922 | 0.90 | MAPT (0.57) | KMT2AMEN1GAAMAPTRAB9A | |
| SCHEMBL29670966 | 0.90 | MAPT (0.57) | KMT2AMEN1GAAMAPTRAB9A | |
| SCHEMBL29670973 | 0.88 | MMP2 (0.43) | KMT2AMEN1MAPTAVPR1ARAB9A | |
| SCHEMBL28722558 | 0.88 | MMP2 (0.43) | KMT2AMEN1MAPTAVPR1ARAB9A | |
| SCHEMBL28708840 | 0.87 | KMT2A (0.55) | KMT2AMEN1MAPTRAB9ANPC1 | |
| SCHEMBL29670955 | 0.87 | KMT2A (0.55) | KMT2AMEN1MAPTRAB9ANPC1 | |
| SCHEMBL29670956 | 0.85 | TP53 (0.50) | KMT2AMEN1GAAMAPTRAB9A | |
| SCHEMBL28705641 | 0.85 | MAPT (0.52) | KMT2AMEN1GAAMAPTTP53 | |
| SCHEMBL29670957 | 0.85 | MAPT (0.52) | KMT2AMEN1GAAMAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114276303-B | Ureido compounds or pharmaceutically acceptable salts thereof, and preparation method and application thereof | 河南大学 | 2023-09-22 | — | — | CN | disclosed |
| CN-114276303-A | Ureido compound or its medicinal salt and its preparing process and application | 河南大学 | 2022-04-05 | — | — | CN | disclosed |