Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 3/20 | 0.46 |
| ▸ | ADAM17 | P78536 | 3/20 | 0.43 |
| ▸ | MMP1 | P03956 | 2/20 | 0.43 |
| ▸ | MMP9 | P14780 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | GPR6 | P46095 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | BRD2 | P25440 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28719007 | 1.00 | MMP2 (0.46) | MMP2ADAM17MMP1MMP9HSD17B10 | |
| SCHEMBL29670976 | 0.84 | MAPT (0.55) | MMP2HSD17B10MAPTDGAT1TP53 | |
| SCHEMBL28719380 | 0.84 | MAPT (0.55) | MMP2HSD17B10MAPTDGAT1TP53 | |
| SCHEMBL28937215 | 0.84 | MMP2 (0.52) | MMP2ADAM17MMP1MMP9HSD17B10 | |
| SCHEMBL29670974 | 0.84 | MMP2 (0.52) | MMP2ADAM17MMP1MMP9HSD17B10 | |
| SCHEMBL28705641 | 0.82 | MAPT (0.52) | MAPTTP53THRBSMN1; SMN2KDM4E | |
| SCHEMBL29670957 | 0.82 | MAPT (0.52) | MAPTTP53THRBSMN1; SMN2KDM4E | |
| SCHEMBL26110619 | 0.81 | MAPK1 (0.45) | MMP2ADAM17MMP1MMP9HSD17B10 | |
| SCHEMBL28722560 | 0.81 | MAPT (0.48) | MMP2MAPTDGAT1TP53THRB | |
| SCHEMBL29670982 | 0.81 | ALDH1A1 (0.57) | POLBMAPTDGAT1TP53NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114276303-B | Ureido compounds or pharmaceutically acceptable salts thereof, and preparation method and application thereof | 河南大学 | 2023-09-22 | — | — | CN | disclosed |
| CN-114276303-A | Ureido compound or its medicinal salt and its preparing process and application | 河南大学 | 2022-04-05 | — | — | CN | disclosed |