Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 4/20 | 0.56 |
| ▸ | RAB9A | P51151 | 4/20 | 0.56 |
| ▸ | TP53 | P04637 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28719037 | 1.00 | ALDH1A1 (0.57) | ALDH1A1MAPK1L3MBTL1HTTNPC1 | |
| SCHEMBL28719380 | 0.89 | MAPT (0.55) | ALDH1A1HTTNPC1RAB9ATP53 | |
| SCHEMBL29670976 | 0.89 | MAPT (0.55) | ALDH1A1HTTNPC1RAB9ATP53 | |
| SCHEMBL29670964 | 0.86 | MAPT (0.48) | ALDH1A1HTTNPC1RAB9ATP53 | |
| SCHEMBL28722560 | 0.86 | MAPT (0.48) | ALDH1A1HTTNPC1RAB9ATP53 | |
| SCHEMBL28719012 | 0.85 | MAPT (0.47) | ALDH1A1MAPK1L3MBTL1HTTNPC1 | |
| SCHEMBL29670966 | 0.85 | MAPT (0.57) | ALDH1A1MAPK1NPC1RAB9ATP53 | |
| SCHEMBL28715922 | 0.85 | MAPT (0.57) | ALDH1A1MAPK1NPC1RAB9ATP53 | |
| SCHEMBL28722558 | 0.85 | MMP2 (0.43) | ALDH1A1MAPK1L3MBTL1HTTNPC1 | |
| SCHEMBL29670973 | 0.85 | MMP2 (0.43) | ALDH1A1MAPK1L3MBTL1HTTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114276303-B | Ureido compounds or pharmaceutically acceptable salts thereof, and preparation method and application thereof | 河南大学 | 2023-09-22 | — | — | CN | disclosed |
| CN-114276303-A | Ureido compound or its medicinal salt and its preparing process and application | 河南大学 | 2022-04-05 | — | — | CN | disclosed |