Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | AVPR1A | P37288 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | GPR6 | P46095 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28722558 | 1.00 | MMP2 (0.43) | MMP2POLBAVPR1AALDH1A1MAPK1 | |
| SCHEMBL29670970 | 0.88 | KMT2A (0.51) | MMP2AVPR1AALDH1A1MAPTMEN1 | |
| SCHEMBL28718270 | 0.88 | KMT2A (0.51) | MMP2AVPR1AALDH1A1MAPTMEN1 | |
| SCHEMBL28719037 | 0.85 | ALDH1A1 (0.57) | POLBALDH1A1MAPK1MAPTLMNA | |
| SCHEMBL29670982 | 0.85 | ALDH1A1 (0.57) | POLBALDH1A1MAPK1MAPTLMNA | |
| SCHEMBL29670976 | 0.83 | MAPT (0.55) | MMP2ALDH1A1MAPTTSHRSMN1; SMN2 | |
| SCHEMBL28719380 | 0.83 | MAPT (0.55) | MMP2ALDH1A1MAPTTSHRSMN1; SMN2 | |
| SCHEMBL29670964 | 0.83 | MAPT (0.48) | MMP2ALDH1A1MAPTSMN1; SMN2HTT | |
| SCHEMBL28722560 | 0.83 | MAPT (0.48) | MMP2ALDH1A1MAPTSMN1; SMN2HTT | |
| SCHEMBL29670966 | 0.82 | MAPT (0.57) | POLBALDH1A1MAPK1MAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114276303-B | Ureido compounds or pharmaceutically acceptable salts thereof, and preparation method and application thereof | 河南大学 | 2023-09-22 | — | — | CN | disclosed |
| CN-114276303-A | Ureido compound or its medicinal salt and its preparing process and application | 河南大学 | 2022-04-05 | — | — | CN | disclosed |