Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29671327 | 0.82 | MAPT (0.43) | NPC1RAB9AHPGDALDH1A1HDAC11 | |
| SCHEMBL29671205 | 0.82 | TRPV4 (0.50) | NPC1RAB9AALDH1A1HDAC11HDAC8 | |
| SCHEMBL29671200 | 0.80 | ATM (0.50) | NPC1RAB9AALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL27020189 | 0.80 | HDAC6 (0.34) | HDAC11HDAC8HDAC6SMN1; SMN2MEN1 | |
| SCHEMBL29671254 | 0.80 | GAA (0.62) | NPC1RAB9AALDH1A1HDAC11HDAC8 | |
| SCHEMBL29899439 | 0.80 | MAPT (0.55) | NPC1RAB9AHPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL29729068 | 0.79 | ALDH1A1 (0.41) | NPC1RAB9AHPGDALDH1A1HDAC11 | |
| SCHEMBL29671191 | 0.77 | SMN1; SMN2 (0.51) | HSD11B1NPC1RAB9AALDH1A1HDAC11 | |
| SCHEMBL29671286 | 0.76 | HDAC6 (0.34) | HDAC11HDAC8HDAC6HDAC3 | |
| SCHEMBL1506643 | 0.75 | ALDH1A1 (0.62) | RAB9AALDH1A1MAPTTP53MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12559454-B2 | Benzenesulfonamide derivatives and uses thereof | 2692372 ONTARIO, INC. (CA) | 2026-02-24 | — | — | US | disclosed |
| US-20220281812-A1 | BENZENESULFONAMIDE DERIVATIVES AND USES THEREOF | 2692372 ONTARIO INC (CA) | 2022-09-08 | — | — | US | disclosed |
| CN-114502533-A | Benzenesulfonamide derivatives and use thereof | 2692372安大略公司 | 2022-05-13 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12559454-B2 | Benzenesulfonamide derivatives and uses thereof | NR2E1, NR2C2, NR3C1 | HSD11B1 1364/4885NPC1 272/4885RAB9A 2966/4885 |
| US-20220281812-A1 | BENZENESULFONAMIDE DERIVATIVES AND USES THEREOF | BCR, ARSA, VHL | HSD11B1 2843/4885NPC1 1221/4885RAB9A 2441/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.