SCHEMBL29672230

SCHEMBL29672230

Nc1ccc(C(=O)Nc2cccc(N)c2)cc1

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 6/20 0.74
MEN1 O00255 3/20 0.67
KMT2A Q03164 3/20 0.67
LMNA P02545 1/20 0.67
POLB P06746 1/20 0.67
PKM P14618 1/20 0.67
APEX1 P27695 1/20 0.67
TDP1 Q9NUW8 1/20 0.67
DDX3X O00571 1/20 0.65
ALDH1A1 P00352 2/20 0.61
KCNK3 O14649 2/20 0.59
KCNK9 Q9NPC2 2/20 0.59
SMN1; SMN2 Q16637 2/20 0.58
MAPT P10636 1/20 0.58
TP53 P04637 2/20 0.54
SIRT1 Q96EB6 1/20 0.53
TOP1 P11387 1/20 0.53
NPC1 O15118 1/20 0.53
MAPK1 P28482 1/20 0.53
RAB9A P51151 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL927121 1.00 PTGS1 (0.74) PTGS1MEN1KMT2ALMNAPOLB
SCHEMBL29568808 0.96 PTGS1 (0.79) PTGS1MEN1KMT2ALMNAPOLB
SCHEMBL8399784 0.96 PTGS1 (0.79) PTGS1MEN1KMT2ALMNAPOLB
SCHEMBL2126663 0.93 MEN1 (0.71) PTGS1MEN1KMT2ALMNAPOLB
SCHEMBL17744817 0.92 PTGS1 (0.64) PTGS1MEN1KMT2ALMNAPOLB
SCHEMBL21295922 0.90 PTGS1 (0.70) PTGS1MEN1KMT2ALMNAPOLB
SCHEMBL394748 0.89 KCNK3 (0.76) PTGS1MEN1KMT2APOLBDDX3X
SCHEMBL26737633 0.89 DDX3X (0.69) PTGS1MEN1KMT2ADDX3XALDH1A1
SCHEMBL22826277 0.88 PTGS1 (0.65) PTGS1MEN1KMT2ALMNAPOLB
SCHEMBL1336220 0.88 PTGS1 (0.68) PTGS1MEN1KMT2ATDP1DDX3X

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114621440-B High-temperature-resistant polyamide-polyetherimide toughening polymer and preparation method thereof 苏州予信天材新材料应用技术有限公司 2024-11-12 CN disclosed
CN-117321118-A Material for melt processing and melt processed product 本州化学工业株式会社 2023-12-29 CN disclosed
CN-110628025-B Polyimide precursor, polyimide, and material for use in production thereof 宇部兴产株式会社 2022-07-12 CN disclosed
CN-114644858-A Pigment dispersion liquid, coloring composition, and method for dispersing pigment 东京应化工业株式会社 2022-06-21 CN disclosed
CN-114644859-A Coloring composition, colored film, and method for forming colored film 东京应化工业株式会社 2022-06-21 CN disclosed