SCHEMBL29672995

SCHEMBL29672995

O=C(O)COC1C=Cc2ccccc21

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGDR2 Q9Y5Y4 1/20 0.41
ALOX15 P16050 1/20 0.39
PAM P19021 1/20 0.35
RET P07949 1/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
LMNA P02545 1/20 0.35
HTR2A P28223 1/20 0.34
POLB P06746 2/20 0.34
GLA P06280 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
HTR6 P50406 1/20 0.34
P2RY2 P41231 1/20 0.34
PTPN7 P35236 2/20 0.33
ALDH1A1 P00352 2/20 0.33
ATM Q13315 1/20 0.33
FFAR1 O14842 1/20 0.33
KDM4E B2RXH2 1/20 0.33
GAA P10253 1/20 0.33
MEN1 O00255 1/20 0.33
MAPT P10636 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31072333 0.78 KDM4E (0.35) PTGDR2RETHTR2APOLBHTR6
SCHEMBL31072332 0.78 KDM4E (0.35) PTGDR2RETHTR2APOLBHTR6
SCHEMBL30931450 0.77 POLB (0.38) PTGDR2RETSMN1; SMN2LMNAHTR2A
SCHEMBL4516491 0.75 RET (0.42) RETSMN1; SMN2LMNAHTR2AHTR6
SCHEMBL6700611 0.75 POLB (0.39) RETSMN1; SMN2LMNAHTR2APOLB
SCHEMBL5718862 0.75 RET (0.39) RETSMN1; SMN2LMNAHTR2AHTR6
SCHEMBL28769795 0.73 POLB (0.36) RETSMN1; SMN2LMNAHTR2APOLB
SCHEMBL18775716 0.73 RET (0.36) RETSMN1; SMN2LMNAHTR2AHTR6
SCHEMBL89374 0.72 POLB (0.49) RETSMN1; SMN2LMNAHTR2APOLB
SCHEMBL8694188 0.72 POLB (0.49) RETSMN1; SMN2LMNAHTR2APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114561277-A Methods and devices for conditioning cell populations for cell therapy 得克萨斯州大学系统董事会 2022-05-31 CN disclosed