Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | RET | P07949 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | CCL2 | P13500 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8697270 | 1.00 | POLB (0.49) | POLBALDH1A1KDM4ERETHPGD | |
| SCHEMBL8694188 | 1.00 | POLB (0.49) | POLBALDH1A1KDM4ERETHPGD | |
| SCHEMBL28304038 | 0.98 | POLB (0.47) | POLBALDH1A1KDM4ERETHPGD | |
| SCHEMBL6700611 | 0.85 | POLB (0.39) | POLBALDH1A1KDM4ERETKMT2A | |
| SCHEMBL30931450 | 0.84 | POLB (0.38) | POLBALDH1A1KDM4ERETKMT2A | |
| SCHEMBL17222502 | 0.83 | POLB (0.37) | POLBALDH1A1KDM4ERETHPGD | |
| SCHEMBL459671 | 0.83 | POLB (0.37) | POLBALDH1A1KDM4ERETHPGD | |
| SCHEMBL15664847 | 0.83 | POLB (0.37) | POLBALDH1A1KDM4ERETKMT2A | |
| SCHEMBL28022821 | 0.82 | POLB (0.39) | POLBALDH1A1KDM4EHPGDKMT2A | |
| SCHEMBL27926152 | 0.82 | ALDH1A1 (0.38) | POLBALDH1A1KDM4ERETHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 4116 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240216311-A1 | FULLY-DILUTABLE, SELF-MICROEMULSIFYING DELIVERY SYSTEMS (SMEDDS) FOR POORLY WATER-SOLUBLE POLAR SOLUTES | THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO (CA) | 2024-07-04 | — | — | US | claimed |
| WO-2024044849-A1 | DILUTABLE COMPOSITIONS AND PROCESSES FOR EXTRACTING AND REFINING POORLY WATER-SOLUBLE POLAR OILS FROM BIOMASS | MICELLAE DELIVERY SYSTEMS INC. (CA) | 2024-03-07 | — | — | WO | claimed |
| US-20230405003-A1 | APPLICATION OF THYMIDINE DERIVATIVE IN PREPARATION OF DRUGS | ONQUALITY PHARMACEUTICALS CHINA LTD. (CN) | 2023-12-21 | — | — | US | claimed |
| EP-4271414-A1 | FULLY-DILUTABLE, SELF-MICROEMULSIFYING DELIVERY SYSTEMS (SMEDDS) FOR POORLY WATER-SOLUBLE POLAR SOLUTES | The Governing Council of the University of Toronto (CA) | 2023-11-08 | — | — | EP | claimed |
| EP-4238571-A1 | APPLICATION OF THYMIDINE DERIVATIVE IN PREPARATION OF DRUGS | OnQuality Pharmaceuticals China Ltd. (CN) | 2023-09-06 | — | — | EP | claimed |
| WO-2022140843-A1 | FULLY-DILUTABLE, SELF-MICROEMULSIFYING DELIVERY SYSTEMS (SMEDDS) FOR POORLY WATER-SOLUBLE POLAR SOLUTES | THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO (CA) | 2022-07-07 | — | — | WO | claimed |
| EP-3512503-A1 | LIPOSOMAL FORMULATIONS | Nanyang Technological University (SG) | 2019-07-24 | — | — | EP | claimed |
| US-20190216735-A1 | LIPOSOMAL FORMULATIONS | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2019-07-18 | — | — | US | claimed |
| US-10076641-B2 | Methods and systems for delivering substances into luminal walls | THE SPECTRANETICS CORPORATION (US) | 2018-09-18 | — | — | US | claimed |
| WO-2018052373-A1 | LIPOSOMAL FORMULATIONS | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2018-03-22 | — | — | WO | claimed |
| US-20050215565-A1 | Composition for and treatment of demyelinating diseases and paralysis by administration of remyelinating agents | BIOGEN MA INC. | 2005-09-29 | — | — | US | claimed |
| US-20050069541-A1 | Composition for and treatment of demyelinating diseases and paralysis by administration of remyelinating agents | BIOGEN IDEC INTERNATIONAL HOLDING LTD. (BM) | 2005-03-31 | — | — | US | claimed |
| EP-1499599-A1 | SUBSTITUTED PYRAZINE DERIVATIVES | Pharmacia & Upjohn Company LLC (US) | 2005-01-26 | — | — | EP | claimed |
| WO-2004066932-A2 | COMPOSITION FOR AND TREATMENT OF DEMYELINATING DISEASES AND PARALYSIS BY ADMINISTRATION OF REMYELINATING AGENTS | ELAN PHARMACEUTICALS INC. (US) | 2004-08-12 | — | — | WO | claimed |
| WO-2004066931-A2 | COMPOSITION FOR AND TREATMENT OF DEMYELINATING DISEASES AND PARALYSIS BY ADMINISTRATION OF REMYELINATING AGENTS | ELAN PHARMACEUTICALS INC. (US) | 2004-08-12 | — | — | WO | claimed |
| US-20030212123-A1 | COX-2 selective carprofen for treating pain and inflammation in dogs | PFIZER INC. | 2003-11-13 | — | — | US | claimed |
| WO-2003091225-A1 | SUBSTITUTED PYRAZINE DERIVATIVES | PHARMACIA & UPJOHN COMPANY (US) | 2003-11-06 | — | — | WO | claimed |
| US-20030176421-A1 | PROKINETIC AGENTS FOR TREATING GASTRIC HYPOMOTILITY AND RELATED DISORDERS | WATSON JOHN W (US) | 2003-09-18 | — | — | US | claimed |
| EP-0642336-A1 | USE OF NSIAD IN THE TREATMENT OF DEMENTIA | UNIVERSITY OF BRITISH COLUMBIA (CA) | 1995-03-15 | — | — | EP | claimed |
| WO-1993024115-A1 | ANTI-RHEUMATOID ARTHRITIC DRUGS IN THE TREATMENT OF DEMENTIA | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 1993-12-09 | — | — | WO | claimed |