Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 1/20 | 1.00 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 3/20 | 0.50 |
| ▸ | CA5A | P35218 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | MMP1 | P03956 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.47 |
| ▸ | MMP8 | P22894 | 1/20 | 0.47 |
| ▸ | MMP13 | P45452 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29481767 | 1.00 | PRMT5 (1.00) | PRMT5WDR77KMT2AGAAHTT | |
| SCHEMBL336603 | 1.00 | PRMT5 (1.00) | PRMT5WDR77KMT2AGAAHTT | |
| SCHEMBL29476299 | 1.00 | PRMT5 (1.00) | PRMT5WDR77KMT2AGAAHTT | |
| SCHEMBL336605 | 1.00 | PRMT5 (1.00) | PRMT5WDR77KMT2AGAAHTT | |
| SCHEMBL30301224 | 1.00 | PRMT5 (1.00) | PRMT5WDR77KMT2AGAAHTT | |
| SCHEMBL28711197 | 0.90 | PRMT5 (0.81) | PRMT5WDR77KMT2AGAAHTT | |
| SCHEMBL29481804 | 0.90 | PRMT5 (0.81) | PRMT5WDR77KMT2AGAAHTT | |
| SCHEMBL29502671 | 0.90 | PRMT5 (0.81) | PRMT5WDR77KMT2AGAAHTT | |
| SCHEMBL28692108 | 0.90 | PRMT5 (0.81) | PRMT5WDR77KMT2AGAAHTT | |
| SCHEMBL8265917 | 0.88 | PRMT5 (0.79) | PRMT5WDR77KMT2AGAAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 779 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118126009-A | Coumarin derivative, preparation method and application | 成都纽瑞特医疗科技股份有限公司 | 2024-06-04 | — | — | CN | claimed |
| EP-2860175-B1 | METHOD FOR PRODUCING 4,4,7-TRIFLUORO-1,2,3,4-TETRAHYDRO-5H-1-BENZAZEPINE COMPOUND AND INTERMEDIATE FOR SYNTHESIS THEREOF | TACURION (US) | 2017-11-29 | — | — | EP | claimed |
| US-9598373-B2 | Method for producing 4,4,7-trifluoro-1,2,3,4-tetrahydro-5H-1-benzazepine compound and intermediate used in the method | TACURION (US) | 2017-03-21 | — | — | US | claimed |
| US-20150141641-A1 | METHOD FOR PRODUCING 4,4,7-TRIFLUORO-1,2,3,4-TETRAHYDRO-5H-1-BENZAZEPINE COMPOUND AND INTERMEDIATE USED IN THE METHOD | ASTELLAS PHARMA INC. (JP) | 2015-05-21 | — | — | US | claimed |
| EP-2860175-A1 | METHOD FOR PRODUCING 4,4,7-TRIFLUORO-1,2,3,4-TETRAHYDRO-5H-1-BENZAZEPINE COMPOUND AND INTERMEDIATE FOR SYNTHESIS THEREOF | Astellas Pharma Inc. (JP) | 2015-04-15 | — | — | EP | claimed |
| WO-2014140220-A1 | PROCESS FOR THE PREPARATION OF (2,3-DIHYDRO-BENZO[B][1,4]DIOXIN-2-YL) METHANOL DERIVATIVES | JANSSEN PHARMACEUTICA, N.V. (BE) | 2014-09-18 | — | — | WO | claimed |
| US-20140275576-A1 | PROCESS FOR THE PREPARATION OF (2,3-DIHYDRO-BENZO[B][1,4]DIOXIN-2-YL) METHANOL DERIVATIVES | JANSSEN PHARMACEUTICA NV (BE) | 2014-09-18 | — | — | US | claimed |
| US-7038062-B2 | Synthesis of cyclic trithiocarbonates from epoxides | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2006-05-02 | — | — | US | claimed |
| US-20060004210-A1 | SYNTHESIS OF CYCLIC TRITHIOCARBONATES FROM EPOXIDES | GOODYEAR TIRE & RUBBER COMPANY, THE | 2006-01-05 | — | — | US | claimed |
| US-20260027106-A1 | PRMT5 INHIBITORS AND USES THEREOF | Epizyme, Inc. | 2026-01-29 | — | — | US | disclosed |
| US-12528827-B2 | Tricyclic heteroaryl-substituted quinoline and azaquinoline compounds as PAR4 inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2026-01-20 | — | — | US | disclosed |
| US-20250195480-A1 | MACROCYCLIC AZOLOPYRIDINE DERIVATIVES AS EED AND PRC2 MODULATORS | Fulcrum Therapeutics, Inc. | 2025-06-19 | — | — | US | disclosed |
| US-12331035-B2 | Bicyclic compound and use thereof | SK BIOPHARMACEUTICALS CO., LTD. (KR) | 2025-06-17 | — | — | US | disclosed |
| US-20250171420-A1 | MOLECULAR GLUE DEGRADERS AND METHODS OF USING THE SAME | MONTE ROSA THERAPEUTICS AG (CH) | 2025-05-29 | — | — | US | disclosed |
| EP-0454385-A1 | Process for preparing optically active isomers of 6-substituted purinyl piperazine derivatives | ORTHO PHARMACEUTICAL CORPORATION (US) | 1991-10-30 | — | — | EP | disclosed |
| US-5053338-A | Hydrolysis of ester to obtain an optically enriched mixture of a phenol enantiomer | GLAXO INC. (US) | 1991-10-01 | — | — | US | disclosed |
| WO-1991010642-A1 | PROCESS FOR PREPARING HOMOCHIRAL AMINES AND PROCESS FOR PREPARING INTERMEDIATES FOR THE PREPARATION THEREOF, AND THE INTERMEDIATES PREPARED IN ACCORDANCE WITH THIS PROCESS | NOBEL CHEMICALS AB (SE) | 1991-07-25 | — | — | WO | disclosed |
| EP-0412814-A2 | Pyridazinones having cardiotonic and beta blocking activity | GLAXO WELLCOME INC. (US) | 1991-02-13 | — | — | EP | disclosed |
| WO-1988000190-A1 | OPTICALLY ACTIVE DERIVATIVES OF GLYCIDOL | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 1988-01-14 | — | — | WO | disclosed |
| WO-1988000190-A1 | OPTICALLY ACTIVE DERIVATIVES OF GLYCIDOL | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 1988-01-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260027106-A1 | PRMT5 INHIBITORS AND USES THEREOF | PRMT5, PRMT1, PRMT3 | PRMT5 1/4885WDR77 158/4885KMT2A 155/4885 |
| US-20250195480-A1 | MACROCYCLIC AZOLOPYRIDINE DERIVATIVES AS EED AND PRC2 MODULATORS | EED, EZH2, BMI1 | PRMT5 292/4885WDR77 368/4885KMT2A 38/4885 |
| US-20150141641-A1 | METHOD FOR PRODUCING 4,4,7-TRIFLUORO-1,2,3,4-TETRAHYDRO-5H-1-BENZAZEPINE COMPOUND AND INTERMEDIATE USED IN THE METHOD | AVPR2, AVPR1A, AVPR1B | PRMT5 81/4885WDR77 3453/4885KMT2A 1807/4885 |
| US-12331035-B2 | Bicyclic compound and use thereof | PRMT5, PRMT6, PRMT1 | PRMT5 1/4885WDR77 97/4885KMT2A 93/4885 |
| US-20060004210-A1 | SYNTHESIS OF CYCLIC TRITHIOCARBONATES FROM EPOXIDES | TST, CXCR6, CCR6 | PRMT5 1044/4885WDR77 847/4885KMT2A 636/4885 |
| US-20250171420-A1 | MOLECULAR GLUE DEGRADERS AND METHODS OF USING THE SAME | PSMA1, CSNK1G1, CSNK1A1 | PRMT5 3054/4885WDR77 1050/4885KMT2A 366/4885 |
| US-20140275576-A1 | PROCESS FOR THE PREPARATION OF (2,3-DIHYDRO-BENZO[B][1,4]DIOXIN-2-YL) METHANOL DERIVATIVES | CYP1B1, CYP1A1, CYP4B1 | PRMT5 4038/4885WDR77 2902/4885KMT2A 1117/4885 |
| US-12528827-B2 | Tricyclic heteroaryl-substituted quinoline and azaquinoline compounds as PAR4 inhibitors | F2RL3, F2R, PF4 | PRMT5 1562/4885WDR77 4530/4885KMT2A 2733/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.