SCHEMBL336603

SCHEMBL336603

O=[N+]([O-])c1cccc(S(=O)(=O)OCC2CO2)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRMT5 O14744 1/20 1.00
WDR77 Q9BQA1 1/20 1.00
KMT2A Q03164 4/20 0.53
GAA P10253 1/20 0.53
HTT P42858 1/20 0.53
CA2 P00918 3/20 0.50
CA5A P35218 1/20 0.50
MEN1 O00255 3/20 0.49
LMNA P02545 1/20 0.47
MMP2 P08253 2/20 0.47
CA1 P00915 1/20 0.47
MMP1 P03956 1/20 0.47
MMP9 P14780 1/20 0.47
MMP8 P22894 1/20 0.47
MMP13 P45452 1/20 0.47
CA12 O43570 1/20 0.46
CA9 Q16790 1/20 0.46
ALDH1A1 P00352 1/20 0.46
ACHE P22303 1/20 0.45
CYP19A1 P11511 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29481767 1.00 PRMT5 (1.00) PRMT5WDR77KMT2AGAAHTT
SCHEMBL29476299 1.00 PRMT5 (1.00) PRMT5WDR77KMT2AGAAHTT
SCHEMBL336605 1.00 PRMT5 (1.00) PRMT5WDR77KMT2AGAAHTT
SCHEMBL449928 1.00 PRMT5 (1.00) PRMT5WDR77KMT2AGAAHTT
SCHEMBL30301224 1.00 PRMT5 (1.00) PRMT5WDR77KMT2AGAAHTT
SCHEMBL28711197 0.90 PRMT5 (0.81) PRMT5WDR77KMT2AGAAHTT
SCHEMBL29481804 0.90 PRMT5 (0.81) PRMT5WDR77KMT2AGAAHTT
SCHEMBL29502671 0.90 PRMT5 (0.81) PRMT5WDR77KMT2AGAAHTT
SCHEMBL28692108 0.90 PRMT5 (0.81) PRMT5WDR77KMT2AGAAHTT
SCHEMBL8265917 0.88 PRMT5 (0.79) PRMT5WDR77KMT2AGAAHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1305 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119708491-A Polydisulfide polymer material containing hydroxy ester group and preparation method thereof 衢州化工新材料创新研究院 2025-03-28 CN claimed
CN-119330928-A Preparation method of high-purity landiolol hydrochloride 康普药业股份有限公司 2025-01-21 CN claimed
CN-115947720-B Design, preparation and application of beta 3 adrenergic receptor anchoring probe 南京师范大学 2024-03-29 CN claimed
CN-117229210-A Decahydroisoquinoline compound and preparation method and application thereof 中国科学院上海药物研究所 2023-12-15 CN claimed
CN-116211887-A Composition for treating acid-base imbalance 特里赛达公司 2023-06-06 CN claimed
CN-116178220-A Method for preparing (2S) -2- [ [3- (methylsulfonyl L) phenoxy ] methyl ] ethylene oxide 爱斯特(成都)生物制药股份有限公司 2023-05-30 CN claimed
CN-115947720-A Design of beta 3 adrenergic receptor anchoring probe and preparation method and application thereof 南京师范大学 2023-04-11 CN claimed
CN-115505062-A Preparation method of sevelamer carbonate 天和药业股份有限公司 2022-12-23 CN claimed
US-11267924-B2 Crosslinked polydiallymine copolymers for the treatment of type 2 diabetes GENZYME CORPORATION (US) 2022-03-08 US claimed
CN-113855703-A Proton binding polymers for oral administration 特里赛达公司 2021-12-31 CN claimed
WO-2007130463-A2 AMINE CONDENSATION POLYMERS AS PHOSPHATE SEQUESTRANTS GENZYME CORPORATION (US) 2007-11-15 WO claimed
US-7038062-B2 Synthesis of cyclic trithiocarbonates from epoxides THE GOODYEAR TIRE & RUBBER COMPANY (US) 2006-05-02 US claimed
US-20060004210-A1 SYNTHESIS OF CYCLIC TRITHIOCARBONATES FROM EPOXIDES GOODYEAR TIRE & RUBBER COMPANY, THE 2006-01-05 US claimed
EP-0930307-B1 PROCESS FOR THE PREPARATION OF GLYCIDYL ETHERS DAISO CO LTD (JP) 2002-12-04 EP claimed
EP-0930291-B1 PROCESS FOR THE PREPARATION OF 3-AMINO-2-HYDROXY-1-PROPYL ETHERS DAISO CO LTD (JP) 2002-08-14 EP claimed
US-6087512-A Process for preparation of glycidyl ether DAISO CO., LTD. (JP) 2000-07-11 US claimed
US-6057476-A Process for the preparation of 3-amino-2-hydroxy-1-propyl ethers DAISO CO., LTD. (JP) 2000-05-02 US claimed
EP-0930291-A1 PROCESS FOR THE PREPARATION OF 3-AMINO-2-HYDROXY-1-PROPYL ETHERS DAISO CO., LTD. (JP) 1999-07-21 EP claimed
EP-0930307-A1 PROCESS FOR THE PREPARATION OF GLYCIDYL ETHERS DAISO CO., LTD. (JP) 1999-07-21 EP claimed
WO-1988000190-A1 OPTICALLY ACTIVE DERIVATIVES OF GLYCIDOL MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 1988-01-14 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11267924-B2 Crosslinked polydiallymine copolymers for the treatment of type 2 diabetes IAPP, PARP2, ADM2 PRMT5 781/4885WDR77 1253/4885KMT2A 766/4885
US-20060004210-A1 SYNTHESIS OF CYCLIC TRITHIOCARBONATES FROM EPOXIDES TST, CXCR6, CCR6 PRMT5 1044/4885WDR77 847/4885KMT2A 636/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.