Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 1/20 | 0.53 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | PARL | Q9H300 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 5/20 | 0.37 |
| ▸ | CA2 | P00918 | 5/20 | 0.37 |
| ▸ | CA9 | Q16790 | 4/20 | 0.37 |
| ▸ | CA12 | O43570 | 3/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.37 |
| ▸ | CA3 | P07451 | 2/20 | 0.37 |
| ▸ | CA4 | P22748 | 2/20 | 0.37 |
| ▸ | CA6 | P23280 | 2/20 | 0.37 |
| ▸ | CA5A | P35218 | 2/20 | 0.37 |
| ▸ | CA7 | P43166 | 2/20 | 0.37 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.37 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.37 |
| ▸ | ALPL | P05186 | 1/20 | 0.36 |
| ▸ | ALPI | P09923 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9303794 | 1.00 | PRMT5 (0.53) | PRMT5WDR77MEN1KMT2APARL | |
| SCHEMBL9304964 | 0.87 | PRMT5 (0.74) | PRMT5WDR77MEN1KMT2AACHE | |
| SCHEMBL9304971 | 0.87 | PRMT5 (0.74) | PRMT5WDR77MEN1KMT2AACHE | |
| SCHEMBL9645456 | 0.83 | PRMT5 (0.72) | PRMT5WDR77PARLACHECA1 | |
| SCHEMBL2967442 | 0.83 | PRMT5 (0.72) | PRMT5WDR77PARLACHECA1 | |
| SCHEMBL1164097 | 0.83 | PRMT5 (0.72) | PRMT5WDR77PARLACHECA1 | |
| SCHEMBL9305032 | 0.82 | ALDH1A1 (0.48) | PRMT5WDR77MEN1KMT2ACA1 | |
| SCHEMBL9305625 | 0.82 | ALDH1A1 (0.48) | PRMT5WDR77MEN1KMT2ACA1 | |
| SCHEMBL9546855 | 0.81 | PRMT5 (0.44) | PRMT5WDR77MEN1KMT2AACHE | |
| SCHEMBL9304736 | 0.81 | PRMT5 (0.44) | PRMT5WDR77MEN1KMT2AACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5326885-A | Process of preparing enriched enantiomers of glycerol carbonate and derivatives thereof for synthesis of β-blockers | COGNIS, INC. (US) | 1994-07-05 | — | — | US | claimed |
| US-5326885-A | Process of preparing enriched enantiomers of glycerol carbonate and derivatives thereof for synthesis of β-blockers | COGNIS, INC. (US) | 1994-07-05 | — | — | US | disclosed |