Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 11/20 | 0.49 |
| ▸ | HAVCR2 | Q8TDQ0 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | DAO | P14920 | 1/20 | 0.41 |
| ▸ | XDH | P47989 | 5/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29674656 | 0.81 | GAA (0.46) | MPOHAVCR2KDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL11483413 | 0.81 | ALDH1A1 (0.37) | MPOHAVCR2KDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL11146401 | 0.80 | ALDH1A1 (0.48) | KDM4ESMN1; SMN2ALDH1A1TDP1GAA | |
| SCHEMBL11149438 | 0.80 | ALDH1A1 (0.44) | MPOALDH1A1TDP1GAA | |
| SCHEMBL16306669 | 0.78 | MPO (0.52) | MPOALDH1A1TDP1GAAPDE4A | |
| SCHEMBL11149357 | 0.77 | ALDH1A1 (0.44) | SMN1; SMN2ALDH1A1GAAPDE4APDE4B | |
| SCHEMBL11149457 | 0.77 | ALDH1A1 (0.44) | MPOALDH1A1TDP1GAA | |
| SCHEMBL11154419 | 0.77 | ALDH1A1 (0.44) | SMN1; SMN2ALDH1A1TDP1GAA | |
| SCHEMBL11147190 | 0.76 | ALDH1A1 (0.44) | KDM4EALDH1A1TDP1GAA | |
| SCHEMBL29674635 | 0.76 | ALDH1A1 (0.79) | KDM4ESMN1; SMN2ALDH1A1GAAPDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022103280-A1 | METHANOGEN INHIBITORS | PASTORAL GREENHOUSE GAS RESEARCH LTD (NZ) | 2022-05-19 | — | — | WO | disclosed |