Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.36 |
| ▸ | JAK2 | O60674 | 3/20 | 0.33 |
| ▸ | JAK1 | P23458 | 3/20 | 0.33 |
| ▸ | TYK2 | P29597 | 3/20 | 0.33 |
| ▸ | JAK3 | P52333 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 2/20 | 0.31 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24439076 | 1.00 | L3MBTL1 (0.38) | L3MBTL1ALDH1A1PTGS2JAK2JAK1 | |
| SCHEMBL19423831 | 0.91 | L3MBTL1 (0.42) | L3MBTL1ALDH1A1PTGS2JAK2JAK1 | |
| SCHEMBL29674676 | 0.84 | ALDH1A1 (0.42) | L3MBTL1ALDH1A1PTGS2JAK2JAK1 | |
| SCHEMBL24439060 | 0.84 | ALDH1A1 (0.42) | L3MBTL1ALDH1A1PTGS2JAK2JAK1 | |
| SCHEMBL24438871 | 0.75 | ALDH1A1 (0.39) | ALDH1A1 | |
| SCHEMBL31160951 | 0.73 | GCK (0.49) | L3MBTL1ALDH1A1PTGS2GAA | |
| SCHEMBL24440520 | 0.72 | MME (0.36) | L3MBTL1ALDH1A1GAAPOLBNPSR1 | |
| SCHEMBL29603887 | 0.70 | L3MBTL1 (0.39) | L3MBTL1ALDH1A1PTGS2GAAPOLB | |
| SCHEMBL24438895 | 0.70 | ALDH1A1 (0.54) | ALDH1A1JAK2JAK1TYK2JAK3 | |
| SCHEMBL19423834 | 0.69 | KIF11 (0.43) | L3MBTL1ALDH1A1TP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022103280-A1 | METHANOGEN INHIBITORS | PASTORAL GREENHOUSE GAS RESEARCH LTD (NZ) | 2022-05-19 | — | — | WO | disclosed |