Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSTM2 | P28161 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 6/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.49 |
| ▸ | MIF | P14174 | 1/20 | 0.48 |
| ▸ | MYC | P01106 | 3/20 | 0.47 |
| ▸ | MAX | P61244 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 2/20 | 0.46 |
| ▸ | DPP4 | P27487 | 2/20 | 0.46 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.46 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29675064 | 0.99 | GSTM2 (0.58) | GSTM2MEN1KMT2AUSP2HTT | |
| SCHEMBL18924049 | 0.86 | GSTM2 (0.59) | GSTM2MEN1KMT2AUSP2HTT | |
| SCHEMBL31580439 | 0.86 | GSTM2 (0.59) | GSTM2MEN1KMT2AUSP2HTT | |
| SCHEMBL17748305 | 0.86 | GSTM2 (0.58) | GSTM2MEN1KMT2AUSP2HTT | |
| SCHEMBL30892506 | 0.84 | GSTM2 (0.76) | GSTM2MEN1KMT2AUSP2HTT | |
| SCHEMBL30892505 | 0.84 | GSTM2 (0.76) | GSTM2MEN1KMT2AUSP2HTT | |
| SCHEMBL14211653 | 0.81 | GSTM2 (0.56) | GSTM2MEN1KMT2AUSP2HTT | |
| SCHEMBL17758327 | 0.81 | GSTM2 (0.53) | GSTM2MEN1KMT2AUSP2HTT | |
| SCHEMBL29646213 | 0.80 | GSTM2 (0.57) | GSTM2MEN1KMT2AUSP2HTT | |
| SCHEMBL13830198 | 0.80 | GSTM2 (0.54) | GSTM2MEN1KMT2AUSP2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220220373-A1 | FLUORESCENT PROBES FOR MONOACYLGLYCEROL LIPASE (MAGL) | HOFFMANN-LA ROCHE INC. (US) | 2022-07-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220220373-A1 | FLUORESCENT PROBES FOR MONOACYLGLYCEROL LIPASE (MAGL) | MGLL, LPL, LIPA | GSTM2 1161/4885MEN1 1304/4885KMT2A 2826/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.