Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.64 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19538025 | 1.00 | ALDH1A1 (0.64) | ALDH1A1ABCG2HPGDKMT2AMCHR1 | |
| SCHEMBL107309 | 0.82 | HPGD (0.81) | ALDH1A1ABCG2HPGDKMT2ARAB9A | |
| SCHEMBL1042327 | 0.80 | RAB9A (0.78) | ALDH1A1KMT2ARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL29675198 | 0.78 | RAB9A (0.69) | ALDH1A1KMT2ARAB9ANPC1MAPT | |
| SCHEMBL19538014 | 0.78 | RAB9A (0.69) | ALDH1A1KMT2ARAB9ANPC1MAPT | |
| SCHEMBL108077 | 0.78 | LMNA (0.72) | ALDH1A1HPGDKMT2ARAB9ANPC1 | |
| SCHEMBL24355627 | 0.76 | HPGD (0.78) | ALDH1A1ABCG2HPGDKMT2ANPC1 | |
| SCHEMBL5007270 | 0.75 | KDM4E (0.66) | ALDH1A1HPGDKMT2ARAB9ANPC1 | |
| SCHEMBL19538016 | 0.75 | GAA (0.56) | ALDH1A1KMT2ARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL5338191 | 0.74 | MEN1 (0.80) | ALDH1A1HPGDKMT2ARAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109153655-B | Novel N-acylurea derivatives and compositions comprising the same for preventing or treating cardiovascular diseases | 高丽大学校产学协力团 | 2022-09-30 | — | — | CN | claimed |
| CN-109153655-B | Novel N-acylurea derivatives and compositions comprising the same for preventing or treating cardiovascular diseases | 高丽大学校产学协力团 | 2022-09-30 | — | — | CN | disclosed |
| US-20220194928-A1 | NOVEL N-ACYLUREA DERIVATIVE AND COMPOSITION COMPRISING SAME FOR PREVENTION OR TREATMENT OF CARDIOVASCULAR DISEASE | UNIV KOREA RES & BUS FOUND (KR) | 2022-06-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220194928-A1 | NOVEL N-ACYLUREA DERIVATIVE AND COMPOSITION COMPRISING SAME FOR PREVENTION OR TREATMENT OF CARDIOVASCULAR DISEASE | TLN1, TNNI3, PTK2 | ALDH1A1 2072/4885ABCG2 2617/4885HPGD 3550/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.